P18756

PR
Gene name
ets1-b
Protein name
Protein c-ets-1-B
Names
C-ets-1B, XE1-B
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-241 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P18756

Entry ID Method Resolution Chain Position Source
AF-P18756-F1 Predicted AlphaFoldDB

No variants for P18756

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P18756

No associated diseases with P18756

2 regional properties for P18756

Type Name Position InterPro Accession
domain Ets domain 161 - 246 IPR000418
domain Ets1, N-terminal flanking region of Ets domain 1 - 158 IPR045688

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

3 GO annotations of biological process

Name Definition
positive regulation of endothelial cell migration Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
regulation of angiogenesis Any process that modulates the frequency, rate or extent of angiogenesis.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
EFSEPSFITE SYQTLHPISS EELLSLKYES DYPLGLLRDP LQPESLQGDY FTIKQEVVSP
70 80 90 100 110 120
DNMCLGRISR GKLGGQESFE SIESHDSCDR LTQSWSSQSS YNSLQRVPSY DSFDSEDYPP
130 140 150 160 170 180
ALPSHKSKGT FKDYVRDRAE LNKDKPVIPA AALAGYTGSG PIQLWQFLLE LLTDKSCQSF
190 200 210 220 230 240
ISWTGDGWEF KLSDPDEVAR RWGKRKNKPK MNYEKLSRGL RYYYDKNIIH KTAGKRYVYR
250 260
FVCDLQSLLG YVPEELHAML DVKPDTDE