P18357

PR
Gene name
blaR1
Protein name
Regulatory protein BlaR1
Names
Species
Staphylococcus aureus
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

42-113 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

13 structures for P18357

Entry ID Method Resolution Chain Position Source
1XA1 X-ray 180 A A/B/C/D 331-585 PDB
1XA7 X-ray 240 A A/B 331-585 PDB
1XKZ X-ray 175 A A/B/C/D 331-585 PDB
3Q81 X-ray 200 A A/B 332-583 PDB
3Q82 X-ray 210 A A/B 332-583 PDB
3UY6 X-ray 210 A A/B 332-583 PDB
6O9W X-ray 195 A A/B 330-585 PDB
8EXP EM 420 A A/B 1-585 PDB
8EXQ EM 490 A A/B 1-585 PDB
8EXR EM 380 A A/B/C 1-585 PDB
8EXS EM 430 A A/B 1-585 PDB
8EXT EM 460 A A/B 1-585 PDB
AF-P18357-F1 Predicted AlphaFoldDB

No variants for P18357

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P18357

No associated diseases with P18357

2 regional properties for P18357

Type Name Position InterPro Accession
domain Penicillin-binding protein, transpeptidase 374 - 576 IPR001460
domain Peptidase M56 4 - 298 IPR008756

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
penicillin binding Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKLLIMSIV SFCFIFLLLL FFRYILKRYF NYMLNYKVWY LTLLAGLIPF IPIKFSLFKF
70 80 90 100 110 120
NNVNNQAPTV ESKSHDLNHN INTTKPIQEF ATDIHKFNWD SIDNISTVIW IVLVIILSFK
130 140 150 160 170 180
FLKALLYLKY LKKQSLYLNE NEKNKIDTIL FNHQYKKNIV IRKAETIQSP ITFWYGKYII
190 200 210 220 230 240
LIPSSYFKSV IDKRLKYIIL HEYAHAKNRD TLHLIIFNIF SIIMSYNPLV HIVKRKIIHD
250 260 270 280 290 300
NEVEADRFVL NNINKNEFKT YAESIMDSVL NVPFFNKNIL SHSFNGKKSL LKRRLINIKE
310 320 330 340 350 360
ANLKKQSKLI LIFICIFTFL LMVIQSQFLM GQSITDYNYK KPLHNDYQIL DKSKIFGSNS
370 380 390 400 410 420
GSFVMYSMKK DKYYIYNEKE SRKRYSPNST YKIYLAMFGL DRHIINDENS RMSWNHKHYP
430 440 450 460 470 480
FDAWNKEQDL NTAMQNSVNW YFERISDQIP KNYTATQLKQ LNYGNKNLGS YKSYWMEDSL
490 500 510 520 530 540
KISNLEQVIV FKNMMEQNNH FSKKAKNQLS SSLLIKKNEK YELYGKTGTG IVNGKYNNGW
550 560 570 580
FVGYVITNHD KYYFATHLSD GKPSGKNAEL ISEKILKEMG VLNGQ