P18351

PR
Gene name
Protein name
Uncharacterized 27.6 kDa protein
Names
ORF 239
Species
Escherichia coli
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

163-236 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P18351

Entry ID Method Resolution Chain Position Source
AF-P18351-F1 Predicted AlphaFoldDB

No variants for P18351

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P18351

No associated diseases with P18351

1 regional properties for P18351

Type Name Position InterPro Accession
domain Initiator Rep protein 8 - 227 IPR000525

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
DNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.

1 GO annotations of biological process

Name Definition
DNA replication initiation The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDKLLNKKIK VKQSNELTEA AYYLSLKAKR VLWLCLMQTY FTASVSEDDD EMAVLGDSTF
70 80 90 100 110 120
KVKVADYQQI FQVSRNQAIK DVKEGVFELS RSAVIFYPKE GSFDCVARPW LTEAGSRSAR
130 140 150 160 170 180
GIWEIEFNHK LLRYIYGLTN QFTTYSLRDC GSLRNPRTIR LYESLAQFKS SGLWVTTHAW
190 200 210 220 230
LNDRFLLPES QQKNLAELKR SFLDPALKQI NEKTPLLAKY SIDDSGKFLF SIIDKQNPV