P18311

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Enterococcus faecium (Streptococcus faecium)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-221 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P18311

Entry ID Method Resolution Chain Position Source
AF-P18311-F1 Predicted AlphaFoldDB

No variants for P18311

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P18311

No associated diseases with P18311

6 regional properties for P18311

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 285 - 454 IPR000795
domain Small GTP-binding protein domain 287 - 444 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 206 - 255 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 563 - 675 IPR023115
domain Translation initiation factor IF-2, domain II 460 - 555 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNKRIYELA KELNQPSKDV VEKAQQLGIN VKNHMGTITT GDEKKLQQAF KKPQTNKKPA
70 80 90 100 110 120
QQASQKPATN QPNEQKKQET KTKQQKNNRN YQDRGQGSGQ VNQGKNQSTN QNRSNNGGGN
130 140 150 160 170 180
NQNRQGATQS GNQNRQGSTQ GGNQNRQGSN QGGNQNRNNN NNRGKFNNNN RNRFNKKGKK
190 200 210 220 230 240
GKQQTSNKPA VPPRKFRELP EVLEYTEGMN VADIAKKIHR EPAEIIKKLF MLGVMVNQNQ
250 260 270 280 290 300
ALDKDTIELL ATDYGMEPQE KIQVDIADID KFFEPEELNP DTLVSRPPVV TIMGHVDHGK
310 320 330 340 350 360
TTLLDTLRHS RVTSGEAGGI TQHIGAYQID IDGKPITFLD TPGHAAFTSM RARGASITDI
370 380 390 400 410 420
TILVVAADDG VMPQTVEAIN HAKAAGVPII VAVNKIDKPG ANPQHVMQEL SEYELIPEAW
430 440 450 460 470 480
GGETIFVEIS AKFGQNIDEL LEMILLVAEV EDLKADPKQR AIGTVIEARL DKGKGPVTTL
490 500 510 520 530 540
LVQQGTLNVG DPIVVGNTYG RVRVMVNDLG RREKSAGPAT PVEITGLNDV PQAGDRFVVF
550 560 570 580 590 600
EDEKTARAAG EERAKRALLE HRAITSRVTL DNLFESLKEG ELKEVNVIIK ADVQGSAEAL
610 620 630 640 650 660
AASLQKIDVE GVRVKIVHSA VGAINESDVT LAAASNAIII GFNVRPTPQA KIQADNEEVD
670 680 690 700 710 720
IRLHRIIYKA IEEIETAMKG MLDPEFEEKI TGQMIVRETF KVSKVGTIAG AYVTEGYIRR
730 740 750 760 770 780
DSGVRVIRDG IVIYEGQLAS LKRFKDDVKE VKMGYECGAM IEKFNDIKVD DVIEGFIMEE
IKTN