P18193
Gene name |
flaA (TP_0249) |
Protein name |
Flagellar filament outer layer protein |
Names |
Sheath protein |
Species |
Treponema pallidum (strain Nichols) |
KEGG Pathway |
tpa:TP_0249 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P18193
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P18193-F1 | Predicted | AlphaFoldDB |
No variants for P18193
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P18193 | |||||
No associated diseases with P18193
No regional properties for P18193
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P18193 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| outer membrane-bounded periplasmic space | The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. |
| periplasmic flagellum | Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| bacterial-type flagellum-dependent cell motility | Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKKAVVLSAV | ALLSGVCAVA | DESVLIDFAK | LNADIMADKS | GGMTHNRRTV | LDYASLADTS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YTDEQKALMR | SSLAVAQWEV | VLNSSARNPV | AHAASRVIEA | PVSEGAKSFA | GERVLGVRVL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FPTWDSNANA | MIKPAFVIPA | YEVMAQVDDQ | GNVQAPTEEE | KASGKGRFED | GYGVVKNVGV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LKSIAVNTYG | MNYPHGLYVM | MRDQDGEVHR | YFMGYLLFDS | WKELVWNNPS | YISDVRSREV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RLYPVYPAST | PHVVFEGFMV | TRDAAHAGGD | YVGYFKDVKI | IYDKAVLSTV | RDFADEDLWG |
| 310 | 320 | 330 | 340 | ||
| IQARREAERK | RVEVARFGQQ | QVLRYIEQEK | LATEVGFTPS | GGAQRQEEQQ |