P17820

PR
Gene name
dnaK (BSU25470)
Protein name
Chaperone protein DnaK
Names
HSP70, Heat shock 70 kDa protein, Heat shock protein 70
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU25470
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

535-611 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P17820

Entry ID Method Resolution Chain Position Source
AF-P17820-F1 Predicted AlphaFoldDB

No variants for P17820

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P17820

No associated diseases with P17820

3 regional properties for P17820

Type Name Position InterPro Accession
conserved_site Heat shock protein 70, conserved site 7 - 14 IPR018181-1
conserved_site Heat shock protein 70, conserved site 166 - 179 IPR018181-2
conserved_site Heat shock protein 70, conserved site 307 - 321 IPR018181-3

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Secreted
  • Present in the cytoplasm early in growth, as cells become stationary protein also accumulates in the medium; secreted protein is not processed (PubMed:21856851)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent protein folding chaperone Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.
unfolded protein binding Binding to an unfolded protein.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKVIGIDLG TTNSCVAVLE GGEPKVIANA EGNRTTPSVV AFKNGERQVG EVAKRQSITN
70 80 90 100 110 120
PNTIMSIKRH MGTDYKVEIE GKDYTPQEVS AIILQHLKSY AESYLGETVS KAVITVPAYF
130 140 150 160 170 180
NDAERQATKD AGKIAGLEVE RIINEPTAAA LAYGLDKTDE DQTILVYDLG GGTFDVSILE
190 200 210 220 230 240
LGDGVFEVRS TAGDNRLGGD DFDQVIIDHL VSEFKKENGI DLSKDKMALQ RLKDAAEKAK
250 260 270 280 290 300
KDLSGVSSTQ ISLPFITAGE AGPLHLELTL TRAKFEELSS HLVERTMGPV RQALQDAGLS
310 320 330 340 350 360
ASEIDKVILV GGSTRIPAVQ EAIKKETGKE AHKGVNPDEV VALGAAIQGG VITGDVKDVV
370 380 390 400 410 420
LLDVTPLSLG IETMGGVFTK LIDRNTTIPT SKSQVFSTAA DNQTAVDIHV LQGERPMSAD
430 440 450 460 470 480
NKTLGRFQLT DIPPAPRGVP QIEVSFDIDK NGIVNVRAKD LGTGKEQNIT IKSSSGLSDE
490 500 510 520 530 540
EIERMVKEAE ENADADAKKK EEIEVRNEAD QLVFQTEKTL KDLEGKVDEE QVKKANDAKD
550 560 570 580 590 600
ALKAAIEKNE FEEIKAKKDE LQTIVQELSM KLYEEAAKAQ QAQGGANAEG KADDNVVDAE
610
YEEVNDDQNK K