P17608

PR
Gene name
ryh1 (hos1, its6, SPAC4C5.02c)
Protein name
GTP-binding protein ryh1
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC4C5.02c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

101-201 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P17608

Entry ID Method Resolution Chain Position Source
AF-P17608-F1 Predicted AlphaFoldDB

1 variants for P17608

Variant ID(s) Position Change Description Diseaes Association Provenance
I_1194366_A_G 146 L>S No Jeffares_SNPs

No associated diseases with P17608

4 regional properties for P17608

Type Name Position InterPro Accession
domain AAA+ ATPase domain 52 - 185 IPR003593
domain RuvB C-terminal winged helix domain 257 - 326 IPR008823
domain RuvB-like P-loop domain 21 - 179 IPR008824
domain RuvB, AAA lid domain 182 - 255 IPR041445

Functions

Description
EC Number
Subcellular Localization
  • Endosome membrane ; Lipid-anchor
  • Golgi apparatus membrane ; Lipid-anchor
  • Nucleus
  • Cytoplasm, cytosol
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endosome membrane The lipid bilayer surrounding an endosome.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

6 GO annotations of biological process

Name Definition
intra-Golgi vesicle-mediated transport The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
positive regulation of TORC2 signaling Any process that activates or increases the frequency, rate or extent of TORC2 signaling.
protein localization to phagophore assembly site Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).
retrograde transport, endosome to Golgi The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSENYSFSLR KFKLVFLGEQ SVGKTSLITR FMYDQFDNTY QATIGIDFLS KTMYLEDRTV
70 80 90 100 110 120
RLQLWDTAGQ ERFRSLIPSY IRDSSVAIIV YDITNHNSFV NTEKWIEDVR AERGDDVIIV
130 140 150 160 170 180
LVGNKTDLAD KRQVTQEEGE KKAKELKIMH METSAKAGHN VKLLFRKIAQ MLPGMENVET
190 200
QSTQMIDVSI QPNENESSCN C