P17506

PR
Gene name
Protein name
Elongation factor 1-alpha
Names
EF-1-alpha, 42Sp50, Thesaurin A
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:397889
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

258-327 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P17506

Entry ID Method Resolution Chain Position Source
AF-P17506-F1 Predicted AlphaFoldDB

No variants for P17506

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P17506

No associated diseases with P17506

4 regional properties for P17506

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 8 - 245 IPR000795
domain Translation elongation factor EFTu/EF1A, C-terminal 337 - 444 IPR004160
domain Translation elongation factor EFTu-like, domain 2 263 - 328 IPR004161
conserved_site Tr-type G domain, conserved site 64 - 79 IPR031157

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDKAPQKTH LNIVIIGHVD SGKSTTTGHL IYKCGGFDPR ALEKVEAAAA QLGKSSFKFA
70 80 90 100 110 120
WILDKLKAER ERGITIDISL WKFQTNRFTI TIIDAPGHRD FIKNMITGTS QADVALLVVS
130 140 150 160 170 180
AATGEFEAGV SRNGQTREHA LLAYTMGVKQ LIVCVNKMDL TDPPYSHKRF DEVVRNVMVY
190 200 210 220 230 240
LKKIGYNPAT IPFVPVSGWT GENISSPSQK MGWFKGWKVK RKDGFTKGQS LLEVLDALVP
250 260 270 280 290 300
PVRPANKPLR LPLQDVYKIG GIGTVPVGKI ETGILKPGMT ISFAPSGFSA EVKSIEMHHE
310 320 330 340 350 360
PLQMAFPGFN IGFNVKNIAV KSLKRGNVAG NSKSDPPTEA SSFTAQVIIL NHPGFIKAGY
370 380 390 400 410 420
SPVIDCHTAH ITCQFAELQE KIDRRTGKKL EDNPGLLKSG DAAIITLKPI KPFCVERFFD
430 440 450 460
YPPLGRFAAR DLKQTVAVGV VKSVEHKAGA AARRQVQKPV LVK