P16533

PR
Gene name
lktC
Protein name
Leukotoxin-activating lysine-acyltransferase LktC serotype A1
Names
Leukotoxin C, Toxin-activating protein C
Species
Mannheimia haemolytica (Pasteurella haemolytica)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

106-167 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P16533

Entry ID Method Resolution Chain Position Source
AF-P16533-F1 Predicted AlphaFoldDB

No variants for P16533

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P16533

No associated diseases with P16533

6 regional properties for P16533

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 469 - 704 IPR003439
domain AAA+ ATPase domain 495 - 681 IPR003593
domain Peptidase C39, bacteriocin processing 2 - 130 IPR005074
domain ABC transporter type 1, transmembrane domain 159 - 437 IPR011527
conserved_site ABC transporter-like, conserved site 607 - 621 IPR017871
domain Peptidase C39-like A 9 - 126 IPR039395

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
acyltransferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).

2 GO annotations of biological process

Name Definition
hemolysis in another organism The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.
toxin metabolic process The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNQSYFNLLG NITWLWMNSS LHKEWSCELL ARNVIPAIEN EQYMLLIDNG IPIAYCSWAD
70 80 90 100 110 120
LNLETEVKYI KDINSLTPEE WQSGDRRWII DWVAPFGHSQ LLYKKMCQKY PDMIVRSIRF
130 140 150 160
YPKQKELGKI AYFKGGKLDK KTAKKRFDTY QEELATALKN EFNFIKK