Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P16482
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P16482-F1 | Predicted | AlphaFoldDB |
No variants for P16482
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P16482 | |||||
No associated diseases with P16482
4 regional properties for P16482
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Sugar transporter, conserved site | 89 - 105 | IPR005829-1 |
| conserved_site | Sugar transporter, conserved site | 139 - 164 | IPR005829-2 |
| conserved_site | Sugar transporter, conserved site | 307 - 324 | IPR005829-3 |
| domain | Major facilitator superfamily domain | 29 - 437 | IPR020846 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| symporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| citrate metabolic process | The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPTARCSMRA | SSTAPVRMMA | TAGGARIGAI | LRVTSGNFLE | QFDFFLFGFY | ATYIAHTFFP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ASSEFASLMM | TFAVFGAGFL | MRPIGAIVLG | AYIDKVGRRK | GLIVTLSIMA | TGTFLIVLIP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SYQTIGLWAP | LLVLIGRLLQ | GFSAGAELGG | VSVYLAEIAT | PGRKGFYTSW | QSGSQQVAIM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VAAAMGFALN | AVLEPSAISD | WGWRIPFLFG | VLIVPFIFIL | RRKLEETQEF | TARRHHLAMR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QVFATLLANW | QVVIAGMMMV | AMTTTAFYLI | TVYAPTFGKK | VLMLSASDSL | LVTLLVAISN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FFWLPVGGAL | SDRFGRRSVL | IAMTLLALAT | AWPALTMLAN | APSFLMMLSV | LLWLSFIYGM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YNGAMIPALT | EIMPAEVRVA | GFSLAYSLAT | AVFGGFTPVI | STALIEYTGD | KASPGYWMSF |
| 430 | 440 | ||||
| AAICGLLATC | YLYRRSAVAL | QTAR |