P16465

PR
Gene name
hpmB
Protein name
Hemolysin transporter protein HpmB
Names
Species
Proteus mirabilis
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-101 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P16465

Entry ID Method Resolution Chain Position Source
AF-P16465-F1 Predicted AlphaFoldDB

No variants for P16465

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P16465

No associated diseases with P16465

4 regional properties for P16465

Type Name Position InterPro Accession
domain Haemolysin activator HlyB, C-terminal 207 - 520 IPR005565
domain Polypeptide-transport-associated, ShlB-type 77 - 150 IPR013686
domain POTRA domain 77 - 150 IPR034746
domain ShlB, POTRA domain 159 - 202 IPR035251

Functions

Description
EC Number
Subcellular Localization
  • Cell outer membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell outer membrane A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
pore complex A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids.

1 GO annotations of molecular function

Name Definition
porin activity Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.

3 GO annotations of biological process

Name Definition
hemolysis in another organism The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.
ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKKVVLLTL LSCFSTSGLS ANETGNLGSI SESRRALQDS QREINQLIEQ NRYQQLQEKA
70 80 90 100 110 120
VNISPTPTLI TESEHCLPIK GVYIQGITLL TEKDLNSLSP LPDQCIKSAD INRLVKELTQ
130 140 150 160 170 180
RYLQHGYITA RIQFLRPNQH GELGLYAIEG FVERIEGGDR GVNTTLLFPR IKGQPLKLAT
190 200 210 220 230 240
LDQGLDQANR LQSNKVTVDI LPGTELGGSV IKLSNQRKSP WHLNIASDNY GQKNSGRWLI
250 260 270 280 290 300
RTNASLDSPL GLSDFVSLNA NITTDNPNTR FNRAYTLLYS IPYGGFTFSS FGSYSEYQFH
310 320 330 340 350 360
QKLQTRTVNL YGDTTQVGIR GDYAFSRSQK QIDTLNIQVT HKRIRNYFSQ IRLDLSSPKL
370 380 390 400 410 420
TTIELGINHL QIIPNGVLST NLSVEKAVGW FGAEETPYIA NGNGNDYRFT KVKLFTNWYQ
430 440 450 460 470 480
RFSLWHSTFL FNSTFLGQYS HDTLPGVEWL SLTDKNAIRG FDQSTLSGDN GGYLRNTLSY
490 500 510 520 530 540
PYRLNHFSIT PRIGVDIGQV KQHGNYKGWQ GGYGLSSGLN IQYQQAQLDL EVAKGELLYH
550 560
QTNSNKTKDP TQLLVKFSYL F