P16425

PR
Gene name
R1A1-element\ORF2
Protein name
Putative 115 kDa protein in type-1 retrotransposable element R1DM
Names
ORF 2, Putative 115 kDa protein in type I retrotransposable element R1DM
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

234-329 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P16425

Entry ID Method Resolution Chain Position Source
AF-P16425-F1 Predicted AlphaFoldDB

No variants for P16425

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P16425

No associated diseases with P16425

2 regional properties for P16425

Type Name Position InterPro Accession
domain Reverse transcriptase domain 479 - 741 IPR000477
domain Endonuclease/exonuclease/phosphatase 97 - 221 IPR005135

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

1 GO annotations of biological process

Name Definition
DNA biosynthetic process The biosynthetic process resulting in the formation of DNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
TLMFSFIQAN CGRGRAATIE LGVRLRRSES MFALVQEPYL GGDEMDVLPE GMRVFTDRRG
70 80 90 100 110 120
KAAILVDHQE AICMPVETLT TDYGVCLVVK GSFGSIFLCA AYCQFDAPLE PYLRYMDAVL
130 140 150 160 170 180
LQASRTPAIL GLDANAVSPM WLSKLSRHAE GQANYRRGEL LSEWMLEARV AALNQSTEVY
190 200 210 220 230 240
TFDNHRATSD IDVTIVNEAA SMWATYEWRV DEWELSDHNI ITVVAEPTTA RSVESIAPVP
250 260 270 280 290 300
SWNFSNARWR LFKEEMVSRI AELPENFSES PLDQQVSTLR SIVHSVCDTA LGRKLTRSPS
310 320 330 340 350 360
RRARWWTADL CAARREVRRL RRLLQDGRRR DDDAAVELVV VELRRASAYY KKLIGRAKMD
370 380 390 400 410 420
DWKRFVGDHA DDPWGRVYKI CRGRRKCTEI GCLRVNGELI TDWGDCARVL LRNFFPVAES
430 440 450 460 470 480
EAPTAIAEEV PPALEVFEVD TCVARLKSRR SPGLDGINGT ICKAVWRAIP EHLASLFSRC
490 500 510 520 530 540
IRLGYFPAEW KCPRVVSLLK GPDKDKCEPS SYRGICLLPV FGKVLEAIMV NRVREVLPEG
550 560 570 580 590 600
CRWQFGFRQG RCVEDAWRHV KSSVGASAAQ YVLGTFVDFK GAFDNVEWSA ALSRLADLGC
610 620 630 640 650 660
REMGLWQSFF SGRRAVIRSS SGTVEVPVTR GCPQGSISGP FIWDILMDVL LQRLQPYCQL
670 680 690 700 710 720
SAYADDLLLL VEGNSRAVLE EKGAQLMSIV ETWGAEVGDC LSTSKTVIML LKGALRRAPT
730 740 750 760 770 780
VRFAGRNLPY VRSCRYLGIT VSEGMKFLTH IASLRQRMTG VVGALARVLR ADWGFSPRAR
790 800 810 820 830 840
RTIYDGLMAP CVLFGAPVWY DTAEQVAAQR RLASCQRLIL LGCLSVCRTV STVALQVLGG
850 860 870 880 890 900
APPLDLAAKL LAIKYKLKRG FPLEENDWLY GEDIACLSWE QRKTRLEECL IQSWQNRWDD
910 920 930 940 950 960
DSEPGRVTHR FIPYVTLAYR DPSFGFSMRT SFLLTGHGSF NAFLHGRALS DTTACACGDP
970 980 990 1000 1010 1020
YEDWMHILCA CPLYADLRDL DGLGVQRLGE NWIFEGILDD QEKTQRLAMF AEEVFLRRRA
L