P16266
Gene name |
anfD |
Protein name |
Nitrogenase iron-iron protein alpha chain |
Names |
Dinitrogenase 3 subunit alpha, Nitrogenase component I |
Species |
Azotobacter vinelandii |
KEGG Pathway |
|
EC number |
1.18.6.1: With dinitrogen as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P16266
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 8BOQ | X-ray | 155 A | A/D | 2-516 | PDB |
| AF-P16266-F1 | Predicted | AlphaFoldDB |
No variants for P16266
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P16266 | |||||
No associated diseases with P16266
3 regional properties for P16266
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Nitrogenase component 1, conserved site | 68 - 75 | IPR000318-1 |
| conserved_site | Nitrogenase component 1, conserved site | 136 - 150 | IPR000318-2 |
| domain | Nitrogenase/oxidoreductase, component 1 | 49 - 447 | IPR000510 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.18.6.1 | With dinitrogen as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| carbonyl sulfide nitrogenase activity | Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide. |
| iron-sulfur cluster binding | Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms. |
| metal ion binding | Binding to a metal ion. |
| nitrogenase activity | Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| nitrogen fixation | The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPHHEFECSK | VIPERKKHAV | IKGKGETLAD | ALPQGYLNTI | PGSISERGCA | YCGAKHVIGT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PMKDVIHISH | GPVGCTYDTW | QTKRYISDND | NFQLKYTYAT | DVKEKHIVFG | AEKLLKQNII |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EAFKAFPQIK | RMTIYQTCAT | ALIGDDINAI | AEEVMEEMPE | VDIFVCNSPG | FAGPSQSGGH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HKINIAWINQ | KVGTVEPEIT | GDHVINYVGE | YNIQGDQEVM | VDYFKRMGIQ | VLSTFTGNGS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YDGLRAMHRA | HLNVLECARS | AEYICNELRV | RYGIPRLDID | GFGFKPLADS | LRKIGMFFGI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EDRAKAIIDE | EVARWKPELD | WYKERLMGKK | VCLWPGGSKL | WHWAHVIEEE | MGLKVVSVYI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KFGHQGDMEK | GIARCGEGTL | AIDDPNELEG | LEALEMLKPD | IILTGKRPGE | VAKKVRVPYL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NAHAYHNGPY | KGFEGWVRFA | RDIYNAIYSP | IHQLSGIDIT | KDNAPEWGNG | FRTRQMLSDG |
| 490 | 500 | 510 | |||
| NLSDAVRNSE | TLRQYTGGYD | SVSKLREREY | PAFERKVG |