P15496

PR
Gene name
IDI1
Protein name
Isopentenyl-diphosphate delta-isomerase
Names
Allergen Bet v I-A, Isopentenyl pyrophosphate isomerase, IPP isomerase
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YPL117C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-90 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P15496

Entry ID Method Resolution Chain Position Source
AF-P15496-F1 Predicted AlphaFoldDB

2 variants for P15496

Variant ID(s) Position Change Description Diseaes Association Provenance
s16-328490 80 D>E No SGRP
s16-328381 117 E>K No SGRP

No associated diseases with P15496

1 regional properties for P15496

Type Name Position InterPro Accession
domain NUDIX hydrolase domain 102 - 259 IPR000086

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
isopentenyl-diphosphate delta-isomerase activity Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.
metal ion binding Binding to a metal ion.

4 GO annotations of biological process

Name Definition
dimethylallyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.
farnesyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
isopentenyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.
sterol biosynthetic process The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q13907 IDI1 Isopentenyl-diphosphate Delta-isomerase 1 Homo sapiens (Human) PR
10 20 30 40 50 60
MTADNNSMPH GAVSSYAKLV QNQTPEDILE EFPEIIPLQQ RPNTRSSETS NDESGETCFS
70 80 90 100 110 120
GHDEEQIKLM NENCIVLDWD DNAIGAGTKK VCHLMENIEK GLLHRAFSVF IFNEQGELLL
130 140 150 160 170 180
QQRATEKITF PDLWTNTCCS HPLCIDDELG LKGKLDDKIK GAITAAVRKL DHELGIPEDE
190 200 210 220 230 240
TKTRGKFHFL NRIHYMAPSN EPWGEHEIDY ILFYKINAKE NLTVNPNVNE VRDFKWVSPN
250 260 270 280
DLKTMFADPS YKFTPWFKII CENYLFNWWE QLDDLSEVEN DRQIHRML