P15245
Gene name |
|
Protein name |
Phenol hydroxylase |
Names |
PHHY |
Species |
Cutaneotrichosporon cutaneum (Yeast) (Trichosporon cutaneum) |
KEGG Pathway |
ag:AAA34202 |
EC number |
1.14.13.7: With NADH or NADPH as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for P15245
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1FOH | X-ray | 240 A | A/B/C/D | 2-665 | PDB |
| 1PN0 | X-ray | 170 A | A/B/C/D | 1-665 | PDB |
| AF-P15245-F1 | Predicted | AlphaFoldDB |
No variants for P15245
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P15245 | |||||
No associated diseases with P15245
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.13.7 | With NADH or NADPH as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| FAD binding | Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
| phenol 2-monooxygenase activity | Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| phenol-containing compound catabolic process | The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTKYSESYCD | VLIVGAGPAG | LMAARVLSEY | VRQKPDLKVR | IIDKRSTKVY | NGQADGLQCR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TLESLKNLGL | ADKILSEAND | MSTIALYNPD | ENGHIRRTDR | IPDTLPGISR | YHQVVLHQGR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IERHILDSIA | EISDTRIKVE | RPLIPEKMEI | DSSKAEDPEA | YPVTMTLRYM | SDHESTPLQF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GHKTENSLFH | SNLQTQEEED | ANYRLPEGKE | AGEIETVHCK | YVIGCDGGHS | WVRRTLGFEM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IGEQTDYIWG | VLDAVPASNF | PDIRSPCAIH | SAESGSIMII | PRENNLVRFY | VQLQARAEKG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GRVDRTKFTP | EVVIANAKKI | FHPYTFDVQQ | LDWFTAYHIG | QRVTEKFSKD | ERVFIAGDAC |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HTHSPKAGQG | MNTSMMDTYN | LGWKLGLVLT | GRAKRDILKT | YEEERHAFAQ | ALIDFDHQFS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RLFSGRPAKD | VADEMGVSMD | VFKEAFVKGN | EFASGTAINY | DENLVTDKKS | SKQELAKNCV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VGTRFKSQPV | VRHSEGLWMH | FGDRLVTDGR | FRIIVFAGKA | TDATQMSRIK | KFSAYLDSEN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SVISLYTPKV | SDRNSRIDVI | TIHSCHRDDI | EMHDFPAPAL | HPKWQYDFIY | ADCDSWHHPH |
| 610 | 620 | 630 | 640 | 650 | 660 |
| PKSYQAWGVD | ETKGAVVVVR | PDGYTSLVTD | LEGTAEIDRY | FSGILVEPKE | KSGAQTEADW |
| TKSTA |