P15032
Gene name |
recE (b1350, JW1344) |
Protein name |
Exodeoxyribonuclease 8 |
Names |
Exodeoxyribonuclease VIII, EXO VIII |
Species |
Escherichia coli (strain K12) |
KEGG Pathway |
eco:b1350 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P15032
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3H4R | X-ray | 280 A | A | 606-866 | PDB |
| AF-P15032-F1 | Predicted | AlphaFoldDB |
No variants for P15032
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P15032 | |||||
No associated diseases with P15032
1 regional properties for P15032
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Putative exodeoxyribonuclease 8, PDDEXK-like domain | 615 - 850 | IPR024432 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| double-stranded DNA 5'-3' exodeoxyribonuclease activity | Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule. |
| identical protein binding | Binding to an identical protein or proteins. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTKPLFLLR | KAKKSSGEPD | VVLWASNDFE | STCATLDYLI | VKSGKKLSSY | FKAVATNFPV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VNDLPAEGEI | DFTWSERYQL | SKDSMTWELK | PGAAPDNAHY | QGNTNVNGED | MTEIEENMLL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PISGQELPIR | WLAQHGSEKP | VTHVSRDGLQ | ALHIARAEEL | PAVTALAVSH | KTSLLDPLEI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RELHKLVRDT | DKVFPNPGNS | NLGLITAFFE | AYLNADYTDR | GLLTKEWMKG | NRVSHITRTA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SGANAGGGNL | TDRGEGFVHD | LTSLARDVAT | GVLARSMDLD | IYNLHPAHAK | RIEEIIAENK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PPFSVFRDKF | ITMPGGLDYS | RAIVVASVKE | APIGIEVIPA | HVTEYLNKVL | TETDHANPDP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EIVDIACGRS | SAPMPQRVTE | EGKQDDEEKP | QPSGTTAVEQ | GEAETMEPDA | TEHHQDTQPL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DAQSQVNSVD | AKYQELRAEL | HEARKNIPSK | NPVDDDKLLA | ASRGEFVDGI | SDPNDPKWVK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GIQTRDCVYQ | NQPETEKTSP | DMNQPEPVVQ | QEPEIACNAC | GQTGGDNCPD | CGAVMGDATY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| QETFDEESQV | EAKENDPEEM | EGAEHPHNEN | AGSDPHRDCS | DETGEVADPV | IVEDIEPGIY |
| 610 | 620 | 630 | 640 | 650 | 660 |
| YGISNENYHA | GPGISKSQLD | DIADTPALYL | WRKNAPVDTT | KTKTLDLGTA | FHCRVLEPEE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| FSNRFIVAPE | FNRRTNAGKE | EEKAFLMECA | STGKTVITAE | EGRKIELMYQ | SVMALPLGQW |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LVESAGHAES | SIYWEDPETG | ILCRCRPDKI | IPEFHWIMDV | KTTADIQRFK | TAYYDYRYHV |
| 790 | 800 | 810 | 820 | 830 | 840 |
| QDAFYSDGYE | AQFGVQPTFV | FLVASTTIEC | GRYPVEIFMM | GEEAKLAGQQ | EYHRNLRTLS |
| 850 | 860 | ||||
| DCLNTDEWPA | IKTLSLPRWA | KEYAND |