P14657

PR
Gene name
gdhA
Protein name
NADP-specific glutamate dehydrogenase
Names
NADP-GDH
Species
Unknown prokaryotic organism
KEGG Pathway
EC number
1.4.1.4: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P14657

Entry ID Method Resolution Chain Position Source
AF-P14657-F1 Predicted AlphaFoldDB

No variants for P14657

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P14657

No associated diseases with P14657

3 regional properties for P14657

Type Name Position InterPro Accession
domain Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic 6 - 286 IPR006075
conserved_site Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site 142 - 156 IPR017958
domain Asn/Gln amidotransferase 326 - 473 IPR018027

Functions

Description
EC Number 1.4.1.4 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
glutamate dehydrogenase (NADP+) activity Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.

1 GO annotations of biological process

Name Definition
glutamate biosynthetic process The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEYAVSVESF LSSLQRHNPH QPEYLQAVRE VFTSLWPFIE RNPAYREQAL LERLVEPERI
70 80 90 100 110 120
IQFRVSWVDD RGQVQVNRAF RVQFNSAIGP YKGGMRFHPS VNLSILKFLG FEQTFKNALT
130 140 150 160 170 180
TLPMGGGKGG SDFDPKGKSQ GRIMRFCQAL MTELYRHLGP DTDVPAGDIG DGGREVGFMA
190 200 210 220 230 240
GMMKKLSNNT ACVFTGKGLS FGGSLIRPEA TGYGLVYFTD AMLQRHGLGF EGMRVAVSGS
250 260 270 280 290 300
GNVAQYTIEK ALELDARVIT VSDSGGTLVD EDGFTTEKLA HLAEIKNQRY GRVADYAAER
310 320 330 340 350 360
GLTYLAGQQP WNVPVDIALP CATQNELDLE AARVIRNGVK AVAEGANMPT TIQATDAFLD
370 380 390 400 410 420
AGVLFAPGKA ANAAGLATSG LEMAQNAARI GWRAEKVDVR LQHIMADIHH ACVEYGGEGK
430 440
QTHYVHGANI AGFVKVAEAM LAQGVL