AiPD: Autoinhibited Protein Database

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

20-90 (Predicted disordered autoinhibitory region) PR

20-90 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
1E3U	X-ray	166 A	A/B/C/D	21-266	PDB
1E4D	X-ray	180 A	A/B/C/D	21-266	PDB
1EWZ	X-ray	240 A	A/B/C/D	21-266	PDB
1FOF	X-ray	200 A	A/B	20-265	PDB
1K4E	X-ray	200 A	A/B	20-266	PDB
1K4F	X-ray	160 A	A/B	20-266	PDB
1K54	X-ray	170 A	A/B/C/D	21-266	PDB
1K55	X-ray	139 A	A/B/C/D	21-266	PDB
1K56	X-ray	170 A	A/B/C/D	21-266	PDB
1K57	X-ray	190 A	A/B/C/D	21-266	PDB
1K6R	X-ray	230 A	A/B	20-266	PDB
1K6S	X-ray	203 A	A/B	20-266	PDB
2HP5	X-ray	270 A	A/B/C/D	20-266	PDB
2HP6	X-ray	220 A	A/B	20-266	PDB
2HP9	X-ray	250 A	A/B	20-266	PDB
2HPB	X-ray	205 A	A/B	20-266	PDB
2RL3	X-ray	190 A	A/B	20-266	PDB
2WGI	X-ray	285 A	A/B	21-266	PDB
2WGV	X-ray	180 A	A/B	20-266	PDB
2WGW	X-ray	180 A	A/B	20-266	PDB
2WKH	X-ray	179 A	A/B	20-266	PDB
2WKI	X-ray	210 A	A/B	20-266	PDB
2X01	X-ray	190 A	A/B	20-266	PDB
2X02	X-ray	135 A	A/B	20-266	PDB
3LCE	X-ray	200 A	A/B/C/D	21-266	PDB
4S2O	X-ray	170 A	A/B	20-265	PDB
4WZ5	X-ray	160 A	A/B/C/D	20-266	PDB
5FQ9	X-ray	150 A	A/B	20-266	PDB
5MMY	X-ray	188 A	A/B	20-264	PDB
5MNU	X-ray	156 A	A/B	20-265	PDB
5MOX	X-ray	141 A	A/B	20-265	PDB
5MOZ	X-ray	134 A	A/B	20-265	PDB
6RTN	X-ray	217 A	A/B	20-265	PDB
7B3R	X-ray	183 A	A/B	20-265	PDB
7B3S	X-ray	185 A	A/B	20-265	PDB
7B3U	X-ray	160 A	A/B	20-265	PDB
7L5R	X-ray	165 A	A/B	21-266	PDB
7L5T	X-ray	188 A	A/B	21-266	PDB
7L5V	X-ray	130 A	A/B	19-266	PDB
AF-P14489-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
No variants for P14489

Type	Name	Position	InterPro Accession
domain	Penicillin-binding protein, transpeptidase	57 - 259	IPR001460
active_site	Beta-lactamase, class-D active site	65 - 75	IPR002137

		Description
EC Number	3.5.2.6	In cyclic amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
No GO annotations for cellular component

Name	Definition
beta-lactamase activity	Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.
penicillin binding	Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system.

Name	Definition
antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
response to antibiotic	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins