P14229

PR
Gene name
smaIR
Protein name
Type II restriction enzyme SmaI
Names
R.SmaI, Endonuclease SmaI, Type-2 restriction enzyme SmaI
Species
Serratia marcescens
KEGG Pathway
EC number
3.1.21.4: Endodeoxyribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

54-123 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P14229

Entry ID Method Resolution Chain Position Source
AF-P14229-F1 Predicted AlphaFoldDB

No variants for P14229

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P14229

No associated diseases with P14229

No regional properties for P14229

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P14229

Functions

Description
EC Number 3.1.21.4 Endodeoxyribonucleases producing 5'-phosphomonoesters
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
type II site-specific deoxyribonuclease activity Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.

1 GO annotations of biological process

Name Definition
DNA restriction-modification system A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRDDQLFTL WGKLNDRQKD NFLKWMKAFD VEKTYQKTSG DIFNDDFFDI FGDRLITHHF
70 80 90 100 110 120
SSTQALTKTL FEHAFNDSLN ESGVISSLAE SRTNPGHDIT IDSIKVALKT EAAKNISKSY
130 140 150 160 170 180
IHVSKWMELG KGEWILELLL ERFLEHLENY ERIFTLRYFK ISEYKFSYQL VEIPKSLLLE
190 200 210 220 230 240
AKNAKLEIMS GSKQSPKPGY GYVLDENENK KFSLYFDGGA ERKLQIKHLN LEHCIVHGVW
DFILPPP