Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P13989
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7PIK | EM | 268 A | A/B/C/D/E | 1-702 | PDB |
| AF-P13989-F1 | Predicted | AlphaFoldDB |
No variants for P13989
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P13989 | |||||
No associated diseases with P13989
1 regional properties for P13989
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Integrase, catalytic core | 262 - 480 | IPR001584 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromosome | A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| transposase activity | Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA integration | The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome. |
| transposition, DNA-mediated | Any process involved in a type of transpositional recombination which occurs via a DNA intermediate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWQINEVVLF | DNDPYRILAI | EDGQVVWMQI | SADKGVPQAR | AELLLMQYLD | EGRLVRTDDP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YVHLDLEEPS | VDSVSFQKRE | EDYRKILPII | NSKDRFDPKV | RSELVEHVVQ | EHKVTKATVY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KLLRRYWQRG | QTPNALIPDY | KNSGAPGERR | SATGTAKIGR | AREYGKGEGT | KVTPEIERLF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RLTIEKHLLN | QKGTKTTVAY | RRFVDLFAQY | FPRIPQEDYP | TLRQFRYFYD | REYPKAQRLK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SRVKAGVYKK | DVRPLSSTAT | SQALGPGSRY | EIDATIADIY | LVDHHDRQKI | IGRPTLYIVI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DVFSRMITGF | YIGFENPSYV | VAMQAFVNAC | SDKTAICAQH | DIEISSSDWP | CVGLPDVLLA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DRGELMSHQV | EALVSSFNVR | VESAPPRRGD | AKGIVESTFR | TLQAEFKSFA | PGIVEGSRIK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SHGETDYRLD | ASLSVFEFTQ | IILRTILFRN | NHLVMDKYDR | DADFPTDLPS | IPVQLWQWGM |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QHRTGSLRAV | EQEQLRVALL | PRRKVSISSF | GVNLWGLYYS | GSEILREGWL | QRSTDIARPQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| HLEAAYDPVL | VDTIYLFPQV | GSRVFWRCNL | TERSRQFKGL | SFWEVWDIQA | QEKHNKANAK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| QDELTKRREL | EAFIQQTIQK | ANKLTPSTTE | PKSTRIKQIK | TNKKEAVTSE | RKKRAEHLKP |
| 670 | 680 | 690 | 700 | ||
| SSSGDEAKVI | PFNAVEADDQ | EDYSLPTYVP | ELFQDPPEKD | ES |