Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for P13878
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for P13878
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P13878 | |||||
No associated diseases with P13878
No regional properties for P13878
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P13878 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| host cell cytoplasm | The cytoplasm of a host cell. |
| host cell nucleus | A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| endonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. |
| metal ion binding | Binding to a metal ion. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cap snatching | A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs. |
| DNA-templated transcription | The synthesis of an RNA transcript from a DNA template. |
| suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host mRNA transcription by directly inhibiting RNA polymerase II activity. |
| viral RNA genome replication | The replication of a viral RNA genome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKTFAEIAE | TFLEPEAVRI | AKEAVEEYGD | HERKIIQIGI | HFQVCCMFCD | EYLSTNGSDR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FVLIEGRKRG | TAVSLQNELC | KSYDLEPLPF | LCDIFDREEK | QFVEIGITRK | ADDSYFQSKF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GKLGNSCKIF | VFSYDGRLDK | NCEGPMEEQK | LRIFSFLATA | ADFLRKENMF | NEIFLPDNEE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TIIEMKKGKT | FLKLRDESVP | LPFQTYEQMK | DYCEKFKGNP | RELASKVSQM | QSNIKLPIKH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YEQNKFRQIR | LPKGPMAPYT | HKFLMEEAWM | FTKISDPERS | RAGEILIDFF | KKGNLSAIRP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KDKPLQGKYP | IHYKNLWNQI | KAAIADRTMV | ISENDHSEFL | GGIGRASKKI | PEVSLTQDVI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TTEGLKQSEN | KLPEPRSFPK | WFNAEWMWAI | KDSDLTGWVP | MAEYPPADNE | LEDYAEHLNK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TMEGVLQGTN | CAREMGKCIL | TVGALMTECR | LFPGKIKVVP | IYARSKERKS | MQEGLPVPSE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MDCLFGICVK | SKSHLNKDDG | MYTIITFEFS | IREPNLEKHQ | KYTVFEAGHT | TVRMKKGESV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IGREVPLYLY | CRTTALSKIK | NDWLSKARRC | FITTMDTVET | ICLRESAKAE | ENLVEKTLNE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KQMWIGKKNG | ELIAQPLREA | LRVQLVQQFY | FCIYNDSQLE | GFCNEQKKIL | MALEGDKKNK |
| 670 | 680 | 690 | 700 | ||
| SSFGFNPEGL | LEKIEECLIN | NPMCLFMAQR | LNELVIEASK | RGAKFFKID |