Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P13552
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P13552-F1 | Predicted | AlphaFoldDB |
No variants for P13552
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P13552 | |||||
No associated diseases with P13552
7 regional properties for P13552
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 10 - 207 | IPR000795 |
| domain | Translation elongation factor EFTu/EF1A, C-terminal | 302 - 396 | IPR004160 |
| domain | Translation elongation factor EFTu-like, domain 2 | 228 - 297 | IPR004161 |
| domain | Small GTP-binding protein domain | 13 - 149 | IPR005225 |
| conserved_site | Tr-type G domain, conserved site | 54 - 69 | IPR031157 |
| domain | Elongation factor Tu, domain 2 | 215 - 300 | IPR033720 |
| domain | Elongation factor Tu (EF-Tu), GTP-binding domain | 11 - 206 | IPR041709 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation elongation factor activity | Functions in chain elongation during polypeptide synthesis at the ribosome. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARAKFERNK | PHVNIGTIGH | VDHGKTTLTA | AITMTLAASG | GAKARKYDDI | DAAPEEKQRG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ITINTAHVEY | ETEQRHYAHV | DCPGHADYVK | NMITGAAQMD | GAILVVSAAD | GPMPQTREHI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLAKQVGVPS | IVVFLNKADM | VDDEELLELV | ELEVRELLSS | YDFPGDDIPI | VSGSALKALD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FLTENPKTTR | GENDWVDKIH | ALMDEVDAYI | PTPERDIDKG | LLDGLWEDVF | SITGRGTVST |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AGIERGKVKV | GDTVELIGIK | DTRTTTVTGA | EMFQKTLEEG | MAGDNVGLLL | RGIQKNDVQR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GMVIAKPKSI | TPHTKFEAEV | YILKKEEGGR | HTPFFKGYRP | QFYVRTTDVT | GTIDEFTADD |
| 370 | 380 | 390 | 400 | ||
| GSTPEMVIPG | DRINMTVQLI | CPIAIEQGMR | FAIREGGRTV | GAGVVAKILA |