P13528

PR
Gene name
unc-86 (C30A5.7)
Protein name
Transcription factor unc-86
Names
Uncoordinated protein 86
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_C30A5.7
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

317-390 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P13528

Entry ID Method Resolution Chain Position Source
AF-P13528-F1 Predicted AlphaFoldDB

No variants for P13528

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P13528

No associated diseases with P13528

No regional properties for P13528

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P13528

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
RNA polymerase II transcription regulator complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.

5 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.
RNA polymerase II transcription regulatory region sequence-specific DNA binding Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
transcription factor binding Binding to a transcription factor, a protein required to initiate or regulate transcription.

7 GO annotations of biological process

Name Definition
mechanosensory behavior Behavior that is dependent upon the sensation of a mechanical stimulus.
neuron development The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
neuron fate specification The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
positive regulation of transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
response to mechanical stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
sensory perception of smell The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQNTAPVPTT TTASKMQPFN NSLFGSFDDP ILNARAAQVA LADIDVKNVP QLTNPLMRPH
70 80 90 100 110 120
DMFSYSNYFS GIHDTSAATN IYQGLPSSSE PFDASVVVPT SSDDQMTPLQ QVMAMQQSYG
130 140 150 160 170 180
APPPFQYNMT HPFSTTSIAS SNNLARYPIA PPTSDMDTDP RQLETFAEHF KQRRIKLGVT
190 200 210 220 230 240
QADVGKALAH LKMPGVGSLS QSTICRFESL TLSHNNMVAL KPILHSWLEK AEEAMKQKDT
250 260 270 280 290 300
IGDINGILPN TDKKRKRTSI AAPEKRELEQ FFKQQPRPSG ERIASIADRL DLKKNVVRVW
310 320 330 340 350
FCNQRQKQKR DFRSQFRARS AAAVMGPRVM PVLNGNNSNN NLKQGQTTYN GLPGFFD