P13511

PR
Gene name
czcA (Rmet_5980)
Protein name
Cobalt-zinc-cadmium resistance protein CzcA
Names
Cation efflux system protein CzcA
Species
Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans)
KEGG Pathway
rme:Rmet_5980
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

394-463 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P13511

Entry ID Method Resolution Chain Position Source
AF-P13511-F1 Predicted AlphaFoldDB

No variants for P13511

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P13511

No associated diseases with P13511

No regional properties for P13511

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P13511

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
cation transmembrane transporter activity Enables the transfer of cation from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
response to cadmium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFERIISFAI QQRWLVLLAV FGMAGLGIFS YNRLPIDAVP DITNVQVQVN TSAPGYSPLE
70 80 90 100 110 120
TEQRATYPIE VVMAGLPGLE QTRSLSRYGL SQVTVIFKDG TDVYFARQLV NQRIQEAKDN
130 140 150 160 170 180
LPEGVVPAMG PISTGLGEIY LWTVEAEEGA RKADGTAYTP TDLREIQDWV VRPQLRNVPG
190 200 210 220 230 240
VTEINTIGGF NKQYLVAPSL ERLASYGLTL TDVVNALNKN NDNVGAGYIE RRGEQYLVRA
250 260 270 280 290 300
PGQVASEDDI RNIIVGTAQG QPIRIRDIGD VEIGKELRTG AATENGKEVV LGTVFMLIGE
310 320 330 340 350 360
NSRAVSKAVD EKVASINRTM PEGVKIVTVY DRTRLVDKAI ATVKKNLLEG AVLVIVILFL
370 380 390 400 410 420
FLGNIRAALI TATIIPLAML FTFTGMVNYK ISANLMSLGA LDFGIIIDGA VVIVENCVRR
430 440 450 460 470 480
LAHAQEHHGR PLTRSERFHE VFAAAKEARR PLIFGQLIIM IVYLPIFALT GVEGKMFHPM
490 500 510 520 530 540
AFTVVLALLG AMILSVTFVP AAVALFIGER VAEKENRLML WAKRRYEPLL EKSLANTAVV
550 560 570 580 590 600
LTFAAVSIVL CVAIAARLGS EFIPNLNEGD IAIQALRIPG TSLSQSVEMQ KTIETTLKAK
610 620 630 640 650 660
FPEIERVFAR TGTAEIASDL MPPNISDGYI MLKPEKDWPE PKKTHAELLS AIQEEAGKIP
670 680 690 700 710 720
GNNYEFSQPI QLRFNELISG VRSDVAVKIF GDDNNVLSET AKKVSAVLQG IPGAQEVKVE
730 740 750 760 770 780
QTTGLPMLTV KIDREKAARY GLNMSDVQDA VATGVGGRDS GTFFQGDRRF DIVVRLPEAV
790 800 810 820 830 840
RGEVEALRRL PIPLPKGVDA RTTFIPLSEV ATLEMAPGPN QISRENGKRR IVISANVRGR
850 860 870 880 890 900
DIGSFVPEAE AAIQSQVKIP AGYWMTWGGT FEQLQSATTR LQVVVPVALL LVFVLLFAMF
910 920 930 940 950 960
NNIKDGLLVF TGIPFALTGG ILALWIRGIP MSITAAVGFI ALCGVAVLNG LVMLSFIRSL
970 980 990 1000 1010 1020
REEGHSLDSA VRVGALTRLR PVLMTALVAS LGFVPMAIAT GTGAEVQRPL ATVVIGGILS
1030 1040 1050 1060
STALTLLVLP VLYRLAHRKD EDAEDTREPV TQTHQPDQGR QPA