P13398

PR
Gene name
nylA
Protein name
6-aminohexanoate-cyclic-dimer hydrolase
Names
Nylon oligomers-degrading enzyme EI
Species
Flavobacterium sp (strain K172)
KEGG Pathway
ag:BAA05090
EC number
3.5.2.12: In cyclic amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

99-194 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for P13398

Entry ID Method Resolution Chain Position Source
3A2P X-ray 190 A A 1-493 PDB
3A2Q X-ray 180 A A 1-493 PDB
AF-P13398-F1 Predicted AlphaFoldDB

No variants for P13398

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P13398

No associated diseases with P13398

2 regional properties for P13398

Type Name Position InterPro Accession
conserved_site Amidase, conserved site 148 - 179 IPR020556
domain Amidase signature domain 26 - 464 IPR023631

Functions

Description
EC Number 3.5.2.12 In cyclic amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
6-aminohexanoate-cyclic-dimer hydrolase activity Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate.

1 GO annotations of biological process

Name Definition
nylon catabolic process The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKVDLWQDA TAQAELVRSG EISRTELLEA TIAHVQAVNP EINAVIIPLF EKARRESELA
70 80 90 100 110 120
SGPFAGVPYL LKDLTVVSQG DINTSSIKGM KESGYRADHD AYFVQRMRAA GFVLLGKTNT
130 140 150 160 170 180
PEMGNQVTTE PEAWGATRNP WNLGRSVGGS SGGSGAAVAA ALSPVAHGND AAGSVRIPAS
190 200 210 220 230 240
VCGVVGLKPT RGRISPGPLV TDSDNVAGAA HEGLFARSVR DIAALLDVVS GHRPGDTFCA
250 260 270 280 290 300
PTASRPYAQG ISENPGSLRV GVLTHNPVGD FALDPECAAA ARGAAAALAA LGHDVNDAYP
310 320 330 340 350 360
EALGDRSFLK DYSTICDVAI AREIERNGEL IGRPLTEDDV EWTSWEMVKR ADQVTGRAFA
370 380 390 400 410 420
ACVDELRYYA GKVERWWEAG WDLLILPTVT RQTPEIGELM LAKGTDLEGR QSAFISGSLQ
430 440 450 460 470 480
MLAFTVPFNV SGQPAISLPI GMSSDGMPIG VQIVAAYGRE DLLLQVAAQL EGALPWVARR
490
PQLLNPSRKI PAA