P13355
Gene name |
SLC2A1 |
Protein name |
Solute carrier family 2, facilitated glucose transporter member 1 |
Names |
Glucose transporter type 1, erythrocyte/brain, GLUT-1 |
Species |
Oryctolagus cuniculus (Rabbit) |
KEGG Pathway |
ocu:100125988 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P13355
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P13355-F1 | Predicted | AlphaFoldDB |
No variants for P13355
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P13355 | |||||
No associated diseases with P13355
3 regional properties for P13355
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Sugar transporter, conserved site | 128 - 153 | IPR005829-1 |
| conserved_site | Sugar transporter, conserved site | 324 - 340 | IPR005829-2 |
| domain | Major facilitator superfamily domain | 15 - 456 | IPR020846 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cortical actin cytoskeleton | The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| photoreceptor inner segment | The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| glucose transmembrane transporter activity | Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other. |
| protein self-association | Binding to a domain within the same polypeptide. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| glucose transmembrane transport | The process in which glucose is transported across a membrane. |
| photoreceptor cell maintenance | Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light. |
| protein-containing complex assembly | The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEPSSKKVTG | RLMLAVGGAV | LGSLQFGYNT | GVINAPQKVI | EEFYNQTWIH | RYGERILPTT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LTTLWSLSVA | IFSVGGMIGS | FSVGLFVNRF | GRRNSMLMMN | LLAFVSAVLM | GFSKLAKSFE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MLILGRFIIG | VYCGLTTGFV | PMYVGEVSPT | ALRGALGTLH | QLGIVVGILI | AQVFGLDSIM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GNEDLWPLLL | SVIFVPALLQ | CIVLPLCPES | PRFLLINRNE | ENRAKSVLKK | LRGNADVTRD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LQEMKEESRQ | MMREKKVTIL | ELFRSPAYRQ | PILSAVVLQL | SQQLSGINAV | FYYSTSIFEK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AGVQQPVYAT | IGSGIVNTAF | TVVSLFVVER | AGRRTLHLIG | LAGMAACAVL | MTIALALLEQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LPWMSYLSIV | AIFGFVAFFE | VGPGPIPWFI | VAELFSQGPR | PAAVAVAGFS | NWTSNFIVGM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| CFQYVEQLCG | PYVFIIFTVL | LVLFFIFTYF | KVPETKGRTF | DEIASGFRQG | GASQSDKTPE |
| 490 | |||||
| ELFHPLGADS | QV |