P13287

PR
Gene name
US3
Protein name
Serine/threonine-protein kinase US3
Names
Species
Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2)
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-186 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P13287

Entry ID Method Resolution Chain Position Source

No variants for P13287

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P13287

No associated diseases with P13287

2 regional properties for P13287

Type Name Position InterPro Accession
domain Protein kinase domain 191 - 478 IPR000719
active_site Serine/threonine-protein kinase, active site 301 - 313 IPR008271

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Host cytoplasm
  • Host nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell cytoplasm The cytoplasm of a host cell.
host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

3 GO annotations of biological process

Name Definition
modulation by virus of host apoptotic process Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells.
modulation by virus of host chromatin organization Any process in which a virus effects a change in the organization of chromatin in the host.
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MACRKFCGVY RRPDKRQEAS VPPETNTAPA FPASTFYTPA EDAYLAPGPP ETIHPSRPPS
70 80 90 100 110 120
PGEAARLCQL QEILAQMHSD EDYPIVDAAG AEEEDEADDD APDDVAYPED YAEGRFLSMV
130 140 150 160 170 180
SAAPLPGASG HPPVPGRAAP PDVRTCDTGK VGATGFTPEE LDTMDREALR AISRGCKPPS
190 200 210 220 230 240
TLAKLVTGLG FAIHGALIPG SEGCVFDSSH PNYPHRVIVK AGWYASTSHE ARLLRRLNHP
250 260 270 280 290 300
AILPLLDLHV VSGVTCLVLP KYHCDLYTYL SKRPSPLGHL QITAVSRQLL SAIDYVHCKG
310 320 330 340 350 360
IIHRDIKTEN IFINTPENIC LGDFGAACFV RGCRSSPFHY GIAGTIDTNA PEVLAGDPYT
370 380 390 400 410 420
QVIDIWSAGL VIFETAVHTA SLFSAPRDPE RRPCDNQIAR IIRQAQVHVD EFPTHAESRL
430 440 450 460 470 480
TAHYRSRAAG NNRPAWTRPA WTRYYKIHTD VEYLICKALT FDAALRPSAA ELLRLPLFHP
K