Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for P12853
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 6KAC | EM | 270 A | O/o | 1-291 | PDB |
| 6KAD | EM | 340 A | O/o | 1-291 | PDB |
| AF-P12853-F1 | Predicted | AlphaFoldDB |
No variants for P12853
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P12853 | |||||
No associated diseases with P12853
No regional properties for P12853
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P12853 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast thylakoid membrane | The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana. |
| photosystem II oxygen evolving complex | A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ). |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| oxygen evolving activity | Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| photosystem II assembly | The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms. |
| photosystem II stabilization | The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALRAAQSAK | AGVRAARPNR | ATAVVCKAQK | VGQAAAAAAL | ATAMVAGSAN | ALTFDEIQGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TYLQVKGSGI | ANTCPVLESG | TTNLKELKAG | SYKLENFCIE | PTSFTVKEES | QFKGGETEFV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KTKLMTRLTY | TLDAMSGSFK | VGSDGSAELK | EDDGIDYAAT | TVQLPGGERV | AFLFTIKQFD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GKGTLDGIKG | DFLVPSYRGS | SFLDPKGRGG | STGYDNAVAL | PARADAEELL | KENVKITKAL |
| 250 | 260 | 270 | 280 | 290 | |
| KGSAVFSVAK | VDPVTGEIAG | VFESIQPSDT | DLGAKPPKDI | KVTGLWYAQL | K |