P12258

PR
Gene name
T
Protein name
Transposable element Hobo transposase
Names
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

164-249 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P12258

Entry ID Method Resolution Chain Position Source
AF-P12258-F1 Predicted AlphaFoldDB

1 variants for P12258

Variant ID(s) Position Change Description Diseaes Association Provenance
521 T>del No

No associated diseases with P12258

3 regional properties for P12258

Type Name Position InterPro Accession
domain Zinc finger, BED-type 73 - 119 IPR003656
domain HAT, C-terminal dimerisation domain 591 - 643 IPR008906
domain Hermes trasposase, DNA-binding domain 127 - 194 IPR018473

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
metal ion binding Binding to a metal ion.
protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

2 GO annotations of biological process

Name Definition
DNA integration The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPYIMIVEF LCLWSSVSAV NCPFFVFYDA ITSLLGFSII WKPKEKVTIM AEAADFVKNK
70 80 90 100 110 120
INNGTYSVAN KHKGKSVIWS ILCDILKEDE TVLDGWLFCR QCQKVLKFLH KNTSNLSRHK
130 140 150 160 170 180
CCLTLRRPTE LKIVSENDKK VAIEKCTQWV VQDCRPFSAV TGAGFKNLVK FFLQIGAIYG
190 200 210 220 230 240
EQVDVDDLLP DPTTLSRKAK SDAEEKRSLI SSEIKKAVDS GRASATVDMW TDQYVQRNFL
250 260 270 280 290 300
GITFHYEKEF KLCDMILGLK SMNFQKSTAE NILMKIKGLF SEFNVENIDN VKFVTDRGAN
310 320 330 340 350 360
IKKALEGNTR LNCSSHLLSN VLEKSFNEAN ELKKIVKSCK KIVKYCKKSN LQHTLETTLK
370 380 390 400 410 420
SACPTRWNSN YKMMKSILDN WRSVDKILGE ADIHVDFNKS SLKVVVDILG DFERIFKKLQ
430 440 450 460 470 480
TSSSPSICFV LPSISKILEL CEPNILDLSA AALLKERILE NIRKIWMANL SIWHKAAFFL
490 500 510 520 530 540
YPPAAHLQEE DILEIKVFCI SQIQVPISYT LSLESTETPR TPETPETPET PETPETPETP
550 560 570 580 590 600
ETPETPETPE SLESPNLFPK KNKTISSENE FFFPKPVTES NSNFNESPLD EIERYIRQRV
610 620 630 640
PLSQNFEVIE WWKNNANLYP QLSKLALKLL SIPASSAELK ECFP