Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P12254
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P12254-F1 | Predicted | AlphaFoldDB |
No variants for P12254
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P12254 | |||||
No associated diseases with P12254
6 regional properties for P12254
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Nitrite/Sulfite reductase ferredoxin-like domain | 92 - 152 | IPR005117-1 |
| domain | Nitrite/Sulfite reductase ferredoxin-like domain | 338 - 400 | IPR005117-2 |
| binding_site | Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site | 412 - 430 | IPR006066-1 |
| binding_site | Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site | 461 - 479 | IPR006066-2 |
| domain | Nitrite/sulphite reductase 4Fe-4S domain | 162 - 312 | IPR006067-1 |
| domain | Nitrite/sulphite reductase 4Fe-4S domain | 413 - 540 | IPR006067-2 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| sigma factor activity | Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated transcription initiation | The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place. |
| sporulation resulting in formation of a cellular spore | The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVTGVFAALG | FVVKELVFLV | SYVKNNAFPQ | PLSSSEEKKY | LELMAKGDEH | ARNMLIEHNL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RLVAHIVKKF | ENTGEDAEDL | ISIGTIGLIK | GIESYSAGKG | TKLATYAARC | IENEIVITKG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GCIHPSLIRF | NIYGVRIHNG | NFFHDKVNNC | FFIFKSMPPL | FVMNNEILMH | LRALKKTKKD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VSLHDPIGQD | KEGNEISLID | VLKSENEDVI | DTIQLNMELE | KVKQYIDILD | DREKEVIVGR |
| 250 | 260 | 270 | 280 | 290 | |
| FGLDLKKEKT | QREIAKELGI | SRSYVSRIEK | RALMKMFHEF | YRAEKEKRKK | AKGK |