Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P11934
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 4CAT | X-ray | 300 A | A/B | - | PDB |
| AF-P11934-F1 | Predicted | AlphaFoldDB |
No variants for P11934
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P11934 | |||||
No associated diseases with P11934
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| peroxisome | A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| catalase activity | Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O. |
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| hydrogen peroxide catabolic process | The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2). |
| response to oxidative stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| AAAQRRQNDS | SVFLAIMVAA | AVESESSLTD | GDAGALLLQD | ISEWDEVFRF | DRLEAVERAA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HAAAAAAFGA | FVARGDWTAS | AAAAFQAAGK | QIAFMAAFST | VAGAKGSATV | RDADAFAAKF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ASAAALQELV | GNNSPISFFI | FDLLFAAILF | ASKAKAANQA | AFAAAAELAA | ESLFVRLPSL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HQVSFFALAG | FAAVAAHRHM | NGYGSHTFKL | VAKDGSVYCS | KFWYKADQGQ | AAEVWKDAEE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VAAEDVDYFR | DLNFQAEAAG | RYPLWELASQ | VMTFSDFEID | PFNENIPTKV | VPRESVPLIV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DAELLLNRNP | LNMFAEVEQV | FMDVAAASKG | ADEVEDPLIQ | RQFAYIDTHL | SELTASYGIP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VCRPYATVLN | DQEDGARYDD | VQDVLVIAPN | AFSASAVEVQ | IPAAAAFNLA | AARVAAAGDV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RVNAVVEADQ | RKQSRQFWAS | DVNAQKKRLV | DAFRMEVASA | VSASIQVDVT | VEFSFVAAAA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AARIAAAVGS | AAAGALANRR | QIKVIASLAV | LAKADAKVRQ | KNALESSSQA | VAVDAKAAAQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DIVDSSDAAN | VVTVAREFAV | LPQTAAADAA | EFVAAASAKA | FSSFPAMEVI | SVAAAAGAVA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| EPARASLDLN | MAMFFSRIVA | SRGAAANAIA | ALVKASRDGV | FVAAVLAKAA | ANNRAAEAIF |
| KFEVRQAVDA |