Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

2 structures for P11934

Entry ID Method Resolution Chain Position Source
4CAT X-ray 300 A A/B - PDB
AF-P11934-F1 Predicted AlphaFoldDB

No variants for P11934

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P11934

No associated diseases with P11934

2 regional properties for P11934

Type Name Position InterPro Accession
domain Catalase core domain 19 - 396 IPR011614
active_site Catalase active site 50 - 66 IPR024708

Functions

Description
EC Number
Subcellular Localization
  • Peroxisome matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
AAAQRRQNDS SVFLAIMVAA AVESESSLTD GDAGALLLQD ISEWDEVFRF DRLEAVERAA
70 80 90 100 110 120
HAAAAAAFGA FVARGDWTAS AAAAFQAAGK QIAFMAAFST VAGAKGSATV RDADAFAAKF
130 140 150 160 170 180
ASAAALQELV GNNSPISFFI FDLLFAAILF ASKAKAANQA AFAAAAELAA ESLFVRLPSL
190 200 210 220 230 240
HQVSFFALAG FAAVAAHRHM NGYGSHTFKL VAKDGSVYCS KFWYKADQGQ AAEVWKDAEE
250 260 270 280 290 300
VAAEDVDYFR DLNFQAEAAG RYPLWELASQ VMTFSDFEID PFNENIPTKV VPRESVPLIV
310 320 330 340 350 360
DAELLLNRNP LNMFAEVEQV FMDVAAASKG ADEVEDPLIQ RQFAYIDTHL SELTASYGIP
370 380 390 400 410 420
VCRPYATVLN DQEDGARYDD VQDVLVIAPN AFSASAVEVQ IPAAAAFNLA AARVAAAGDV
430 440 450 460 470 480
RVNAVVEADQ RKQSRQFWAS DVNAQKKRLV DAFRMEVASA VSASIQVDVT VEFSFVAAAA
490 500 510 520 530 540
AARIAAAVGS AAAGALANRR QIKVIASLAV LAKADAKVRQ KNALESSSQA VAVDAKAAAQ
550 560 570 580 590 600
DIVDSSDAAN VVTVAREFAV LPQTAAADAA EFVAAASAKA FSSFPAMEVI SVAAAAGAVA
610 620 630 640 650 660
EPARASLDLN MAMFFSRIVA SRGAAANAIA ALVKASRDGV FVAAVLAKAA ANNRAAEAIF
KFEVRQAVDA