P11109
Gene name |
D13 |
Protein name |
Probable exonuclease subunit 2 |
Names |
D13 |
Species |
Escherichia phage T5 (Enterobacteria phage T5) |
KEGG Pathway |
vg:2777609 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for P11109
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for P11109
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P11109 | |||||
No associated diseases with P11109
1 regional properties for P11109
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Rad50/SbcC-type AAA domain | 9 - 193 | IPR038729 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent DNA damage sensor activity | A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis. |
| exonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| degradation of host chromosome by virus | The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis. |
| DNA replication | The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. |
| suppression by virus of host gene expression | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. |
| viral DNA genome replication | The replication of a viral DNA genome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKITIKTLK | FSNVMSYGKD | IVIHFDKNPV | TQLIGGNGLG | KSTIATVIEE | LFYNKNSRGI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KKDALFSWNA | PKKEYDMHAY | FSKDEDEYEL | HKVVKSTAKV | TLIKNGEDIS | GHTATQTYKM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IEEIMGGDFQ | TFTKLIYQSV | GSNLDFLKAT | DATRKAFLVN | LFNQEQYKEM | SETIKADRKE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IANTLNNLQG | QMAVITKILN | GKNNLGTLQE | PVEVPEFDEE | PLAQELTESK | IKAALAKSQE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ANITKLRNLD | KAVQVAEQSF | EPFKNLPAPT | DQNEEISSVT | RDLTIVTSRA | SEVKKRYQKF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KQEASNTECP | TCGTHLNTTA | AQKAMDMARV | EYDPLFKEKQ | SLEAKLEQLK | KEQLEYVAYT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RAKDALDKAV | VARDEFKNSM | SDASFEELNV | QILQVQIRQL | EQEIADGRSK | VAIAKEHNAT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VELANAKYKA | KLEQIEKAEA | EMTEITSKLD | GVSEAVADLD | ILIAALKNLV | GYKLEHSVKV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FEELINKYLS | IMTGGKFALG | FELDETKLQV | VIFNDGNRTS | MENCSTGQQS | RINLATLLAI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RMLLTSISKV | NINLLFLDEV | ISFIDTKGLD | TLVELLNEEE | SLNSIIVSHG | HTHPLAHKIT |
| 610 | |||||
| VKKDAEGFSY | LE |