P11108
Gene name |
D12 |
Protein name |
Probable exonuclease subunit 1 |
Names |
D12 |
Species |
Escherichia phage T5 (Enterobacteria phage T5) |
KEGG Pathway |
vg:2777608 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for P11108
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for P11108
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P11108 | |||||
No associated diseases with P11108
1 regional properties for P11108
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Calcineurin-like phosphoesterase domain, ApaH type | 1 - 132 | IPR004843 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| exonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| degradation of host chromosome by virus | The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis. |
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| suppression by virus of host gene expression | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRILFSADHH | IKLGQDKVPK | EWQKRRFLML | GERLNDIFHN | HNCDLHIAGG | DILDVADPSS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EEIELLEQFM | SRLDHPGKIF | TGNHEMLTKT | ISCLYHYAGV | INKVTSGKWE | VITKPYRSPE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FDIVPYDEIH | KAKWKPPVSK | LCFTHVRGEI | PPHVKPEIDL | TKYNCYDTVI | AGDLHSYTNS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QTIGSTRLLY | PGSPLTTSFH | RERTKGTNGC | FIIDTDTLKV | EWIELGDLPQ | LIRKTIGAGE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EMEPSDYDRV | VYEVTGDVVQ | LKSIKDSDLL | DKKINHRVTK | DAKLNLVDLD | MLGELELYFR |
| 310 | 320 | ||||
| EVEKLSQGDI | DRILARAAKY | VKDYN |