P10908

PR
Gene name
ugpQ (b3449, JW3414)
Protein name
Glycerophosphodiester phosphodiesterase, cytoplasmic
Names
Glycerophosphoryl diester phosphodiesterase, cytoplasmic
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b3449
EC number
3.1.4.46: Phosphoric diester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

65-194 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P10908

Entry ID Method Resolution Chain Position Source
AF-P10908-F1 Predicted AlphaFoldDB

No variants for P10908

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P10908

No associated diseases with P10908

1 regional properties for P10908

Type Name Position InterPro Accession
conserved_site UDP-glycosyltransferase family, conserved site 361 - 404 IPR035595

Functions

Description
EC Number 3.1.4.46 Phosphoric diester hydrolases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
glycerophosphocholine phosphodiesterase activity Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.
glycerophosphodiester phosphodiesterase activity Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.
glycerophosphoinositol glycerophosphodiesterase activity Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+).
magnesium ion binding Binding to a magnesium (Mg) ion.

2 GO annotations of biological process

Name Definition
glycerol metabolic process The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNWPYPRIV AHRGGGKLAP ENTLASIDVG AKYGHKMIEF DAKLSKDGEI FLLHDDNLER
70 80 90 100 110 120
TSNGWGVAGE LNWQDLLRVD AGSWYSKMFK GEPLPLLSQV AERCREHGMM ANIEIKPTTG
130 140 150 160 170 180
TGPLTGKMVA LAARELWAGM TPPLLSSFEI DALEAAQQAA PELPRGLLLD EWRDDWRELT
190 200 210 220 230 240
ARLGCVSIHL NHKLLNKARV MQLKDAGLRI LVYTVNKPQR AAELLRWGVD CICTDAIDVI
GPNFTAQ