P10546

PR
Gene name
Protein name
E1B 55 kDa protein
Names
E1B-55K, E1B protein, large T-antigen, E1B-495R
Species
Human adenovirus F serotype 41 (HAdV-41) (Human adenovirus 41)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-106 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P10546

Entry ID Method Resolution Chain Position Source

No variants for P10546

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P10546

No associated diseases with P10546

1 regional properties for P10546

Type Name Position InterPro Accession
domain Adenovirus E1B protein, N-terminal 1 - 58 IPR006717

Functions

Description
EC Number
Subcellular Localization
  • Host nucleus
  • Host cytoplasm
  • Colocalizes with host TP53 to host PML nuclear bodies
  • PML localization of E1B-55K is necessary for E1B-55K-dependent SUMOylation of TP53
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell cytoplasm The cytoplasm of a host cell.
host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
modulation by virus of host apoptotic process Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MERPNPSVGG IYSGLHDNGP VENPAAEEEG LRLLAGAASA RSGSSAGGGG GGGGGGEPEG
70 80 90 100 110 120
RSGSSNGIVT EPDPEEGTSS GQRGEKRKLE NDGADFLKEL TLSLMSRCYP ESVWWADLED
130 140 150 160 170 180
EFKNGNMNLL YKYGFEQLKT HWMEPWEDWE LALNMFAKVA LRPDTIYTIK KTVNIRKCAY
190 200 210 220 230 240
VIGNGAVVRF QTFDRVVFNC AMQSLGPGVI GMSGVTFNNV RFAADGFNGK VFASTTQLTL
250 260 270 280 290 300
HGVFFQNCSG VCVDSWGRVS ARGCTFVGCW KGLVGQNKSQ MSVKKCVFER CILAMVVEGQ
310 320 330 340 350 360
ARIRHNAGSE NVCFLLLKGT ASVKHNMICG TGHSQLLTCA DGNCQTLKVI HVVSHQRRPW
370 380 390 400 410 420
PVFEHNMLMR CTMHLGARRG MFSPYQSNFC HTKVLMETDA FSRVWWSGVF DLTIELYKVV
430 440 450 460 470
RYDELKARCR PCECGANHIR LYPATLNVTE QLRTDHQMLS CLRTDYESSD ED