P10480
Gene name |
|
Protein name |
Phosphatidylcholine-sterol acyltransferase |
Names |
Glycerophospholipid-cholesterol acyltransferase, GCAT |
Species |
Aeromonas hydrophila |
KEGG Pathway |
|
EC number |
2.3.1.43: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P10480
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P10480-F1 | Predicted | AlphaFoldDB |
No variants for P10480
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P10480 | |||||
No associated diseases with P10480
1 regional properties for P10480
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Histone H2A/H2B/H3 | 1 - 132 | IPR007125 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.43 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| lipase activity | Catalysis of the hydrolysis of a lipid or phospholipid. |
| phosphatidylcholine-sterol O-acyltransferase activity | Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cholesterol metabolic process | The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKKWFVCLLG | LVALTVQAAD | SRPAFSRIVM | FGDSLSDTGK | MYSKMRGYLP | SSPPYYEGRF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SNGPVWLEQL | TNEFPGLTIA | NEAEGGPTAV | AYNKISWNPK | YQVINNLDYE | VTQFLQKDSF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KPDDLVILWV | GANDYLAYGW | NTEQDAKRVR | DAISDAANRM | VLNGAKEILL | FNLPDLGQNP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SARSQKVVEA | ASHVSAYHNQ | LLLNLARQLA | PTGMVKLFEI | DKQFAEMLRD | PQNFGLSDTE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NACYGGSYVW | KPFASRSAST | DSQLSAFNPQ | ERLAIAGNPL | LAQAVASPMA | ARSASTLNCE |
| 310 | 320 | 330 | |||
| GKMFWDQVHP | TTVVHAALSE | PAATFIESQY | EFLAH |