Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for P10271
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for P10271
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P10271 | |||||
No associated diseases with P10271
11 regional properties for P10271
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Retroviral nucleocapsid Gag protein p24, N-terminal | 284 - 409 | IPR000721 |
| domain | Zinc finger, CCHC-type | 526 - 542 | IPR001878-1 |
| domain | Zinc finger, CCHC-type | 553 - 569 | IPR001878-2 |
| active_site | Aspartic peptidase, active site | 768 - 779 | IPR001969 |
| domain | Peptidase A2A, retrovirus, catalytic | 766 - 841 | IPR001995 |
| domain | Beta-retroviral matrix protein | 9 - 92 | IPR003322 |
| domain | Retropepsins | 752 - 849 | IPR018061 |
| domain | dUTPase-like | 620 - 741 | IPR029054 |
| domain | dUTPase, trimeric | 631 - 715 | IPR033704 |
| domain | Retropepsin-like catalytic domain | 757 - 842 | IPR034170 |
| domain | Retroviral nucleocapsid Gag protein p24, C-terminal domain | 410 - 482 | IPR045345 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| viral nucleocapsid | The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| aspartic-type endopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| dUTP diphosphatase activity | Catalysis of the reaction: dUTP + H2O = dUMP + H+ + diphosphate. |
| structural constituent of virion | The action of a molecule that contributes to the structural integrity of a virion. |
| zinc ion binding | Binding to a zinc ion (Zn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
| viral process | A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGVSGSKGQK | LFVSVLQRLL | SERGLHVKES | SAIEFYQFLI | KVSPWFPEEG | GLNLQDWKRV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GREMKRYAAE | HGTDSIPKQA | YPIWLQLREI | LTEQSDLVLL | SAEAKSVTEE | ELEEGLTGLL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| STSSQEKTYG | TRGTAYAEID | TEVDKLSEHI | YDEPYEEKEK | ADKNEEKDHV | RKIKKVVQRK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ENSEGKRKEK | DSKAFLATDW | NDDDLSPEDW | DDLEEQAAHY | HDDDELILPV | KRKVVKKKPQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALRRKPLPPV | GFAGAMAEAR | EKGDLTFTFP | VVFMGESDED | DTPVWEPLPL | KTLKELQSAV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RTMGPSAPYT | LQVVDMVASQ | WLTPSDWHQT | ARATLSPGDY | VLWRTEYEEK | SKEMVQKAAG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KRKGKVSLDM | LLGTGQFLSP | SSQIKLSKDV | LKDVTTNAVL | AWRAIPPPGV | KKTVLAGLKQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GNEESYETFI | SRLEEAVYRM | MPRGEGSDIL | IKQLAWENAN | SLCQDLIRPI | RKTGTIQDYI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RACLDASPAV | VQGMAYAAAM | RGQKYSTFVK | QTYGGGKGGQ | GAEGPVCFSC | GKTGHIRKDC |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KDEKGSKRAP | PGLCPRCKKG | YHWKSECKSK | FDKDGNPLPP | LETNAENSKN | LVKGQSPSPA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| QKGDGVKGSG | LNPEAPPFTI | HDLPRGTPGS | AGLDLSSQKD | LILSLEDGVS | LVPTLVKGTL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| PEGTTGLIIG | RSSNYKKGLE | VLPGVIDSDF | QGEIKVMVKA | AKNAVIIHKG | ERIAQLLLLP |
| 730 | 740 | 750 | 760 | 770 | 780 |
| YLKLPNPVIK | EERGSEGFGS | TSHVHWVQEI | SDSRPMLHIY | LNGRRFLGLL | DTGADKTCIA |
| 790 | 800 | 810 | 820 | 830 | 840 |
| GRDWPANWPI | HQTESSLQGL | GMACGVARSS | QPLRWQHEDK | SGIIHPFVIP | TLPFTLWGRD |
| 850 | |||||
| IMKDIKVRLM | TDSPDDSQDL |