Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P10250

Entry ID Method Resolution Chain Position Source
AF-P10250-F1 Predicted AlphaFoldDB

No variants for P10250

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P10250

No associated diseases with P10250

2 regional properties for P10250

Type Name Position InterPro Accession
conserved_site SecY conserved site 93 - 112 IPR030659-1
conserved_site SecY conserved site 196 - 213 IPR030659-2

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
protein transport by the Sec complex The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVIKKPANKV DKKSTFKSSN KKKNPFKSSF LTKNKDLIYR ILFTLLALII IRLGVYITVP
70 80 90 100 110 120
GVTLDKRFAT DSSRIQFFQL LSTLGGGSIG RFSILALGVS PYITASIIVQ LLSTDVIPVL
130 140 150 160 170 180
TRWSKSGERG RKKLDKLTKI IMIPFALMQA EATIFTLSSQ GLIIPGWDNT NAIANSAFYY
190 200 210 220 230 240
ILIPLVMLGG SFFMLWIADQ ITIKGIGNGI SIVIFIGIII SMPSNLKSTF EYWVSNSGEE
250 260 270 280 290 300
ANIFFSGLLN FMIYISVFLL VILSVVIMNE AERKIPIQQT GSGLTDSSEH TPYLPLKLNN
310 320 330 340 350 360
AGVIPVIFAS AIISTPITIS QIIEAVNPDS GFVIFTRDYL SFNTWWGISI FGILIVLFTF
370 380 390 400 410 420
LYSQVQINPE KIAENFQKSG TFIPGIKPGK DTTKYLTGII NRLSVVGSVF LAIIALLPYV
430 440 450 460 470 480
ISKLTQLPSN LAIGGTGLII CISVAIQTVQ QLKGRIIQQN FIEKKKEKFT NNINKNKTSH
IW