P10047

PR
Gene name
dctB
Protein name
C4-dicarboxylate transport sensor protein DctB
Names
Species
Rhizobium leguminosarum
KEGG Pathway
EC number
2.7.13.3: Protein-histidine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

353-423 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P10047

Entry ID Method Resolution Chain Position Source
AF-P10047-F1 Predicted AlphaFoldDB

No variants for P10047

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P10047

No associated diseases with P10047

7 regional properties for P10047

Type Name Position InterPro Accession
domain Histidine kinase/HSP90-like ATPase 515 - 622 IPR003594
domain Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 403 - 473 IPR003661
domain Signal transduction histidine kinase-related protein, C-terminal 555 - 569 IPR004358-1
domain Signal transduction histidine kinase-related protein, C-terminal 573 - 583 IPR004358-2
domain Signal transduction histidine kinase-related protein, C-terminal 584 - 602 IPR004358-3
domain Signal transduction histidine kinase-related protein, C-terminal 607 - 620 IPR004358-4
domain Histidine kinase domain 412 - 622 IPR005467

Functions

Description
EC Number 2.7.13.3 Protein-histidine kinases
Subcellular Localization
  • Cell inner membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHKSAMSVSQ KLWPSLPLQH RIRRMWWTYA ALAFLAVVAS LWTSGEIGQH RAEAALEEQA
70 80 90 100 110 120
RMDVTLNAAL LRTVLEKYRA LPFVLSQDTA LAAALVGNDA GTFERLSQKL EILAAGTKAA
130 140 150 160 170 180
VIYVIDKDGI AVSASNWREP TSFVGNDYRF REYFQGAVER GQAEHFALGT VSKKPGLYIS
190 200 210 220 230 240
QRISGSNGLL GVVVVKVEFD DVEADWNASG TPSYVVDERG IVLITSLPSW RFMTIGRIAE
250 260 270 280 290 300
DRLTAIRESL QFGAAPLQPL PLDMVRNLGE GLDVVEIVMP GDAGKTRFLD VATSVPATGW
310 320 330 340 350 360
HLQHLVALGP SVDAGIREAR MLALLILLPL LAGAAFLLRR RHTIALRISS EQQAREELER
370 380 390 400 410 420
RVVERTLDLS QARDRLQAEI IGHKSTEQKL QAVQQDLVQA NRLAILGQVA AGVAHEINQP
430 440 450 460 470 480
VATIRAYADN ARTFLDRGQT APAGENLESI AALTERIGSI TEELKTFARK GRGSAEPTGL
490 500 510 520 530 540
KDVIEGAVML LRSRFAGRMD TLDIDLPPDE LQVMGNRIRL EQVLINLLQN ALEAVAPKAG
550 560 570 580 590 600
EGRVEIRTST DAGMVTVTVA DNGPGIPTEI RKGLFTPFNT SKESGLGLGL VISKDIVGDY
610 620
GGRMDVASDS GGTRFIVQLR KA