P0CS56
Gene name |
CNI03070 |
Protein name |
DNA damage-binding protein CMR1 |
Names |
|
Species |
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
KEGG Pathway |
cne:CNI03070 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CS56
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CS56-F1 | Predicted | AlphaFoldDB |
No variants for P0CS56
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0CS56 | |||||
No associated diseases with P0CS56
5 regional properties for P0CS56
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 172 - 217 | IPR001680-1 |
| repeat | WD40 repeat | 245 - 286 | IPR001680-2 |
| repeat | WD40 repeat | 338 - 380 | IPR001680-3 |
| repeat | WD40 repeat | 440 - 478 | IPR001680-4 |
| conserved_site | WD40 repeat, conserved site | 367 - 381 | IPR019775 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to DNA damage stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. |
| regulation of DNA damage checkpoint | Any process that modulates the frequency, rate or extent of a DNA damage checkpoint. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDEETAYELE | RQKTIAENRA | LLDSLGLDPA | GASSPFGSSP | APTSNKTKPK | PKPAPKKRKA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AAVIAVDEGP | RRRSGRIAGL | EADGDAFKAK | VEEEEKEREI | LRVVSRKERE | KVMDVGKMVE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DTPEDEIKDM | EKYLQSIAEL | SNPRTYPAGT | VSAREAYADS | DTVPSEVQRL | KDAFKDMSLK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GNTKVTNERV | FSMCVHPEKT | KTLVLVGDKY | GQLGIWDALG | PPMEKPENED | DTSGLLRAEG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EDEYQEGRVW | RVQAHAKNSI | SCMKVDPVNG | SGLFSTAYDC | SLRHLSFSTL | QSTELFSFQD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EDLLINHFDL | LPSAQEAWMV | DKNGGISHWD | TRESKRESGR | RRWVVQEEGR | GAKLGGVSVN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PLMPHLICTA | GNDQHVRIWD | TRHLFSISSN | LVPSAAAIEE | EEEGTSTLSG | QSSSLPHDTH |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PTRESDYSTV | TSYLASPRGK | GLMRAKWQHG | KSCSSAYWDP | WGRRILTTSY | DDHLRVFNID |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PGSSLVDDRA | VGSLLQPNGF | KPTKVVRHNC | QTGRWLTILR | AQWSLNMEYM | PHFTVGNMKR |
| 550 | 560 | 570 | 580 | 590 | |
| TLDVVSATGE | KIVGLWTDDV | TAVPTVTASH | PNIVDRVVGG | NTSGRIQLWS | SGDHI |