P0CS02
Gene name |
GMT1 (VRG4-1, CNF01620) |
Protein name |
GDP-mannose transporter 1 |
Names |
GMT 1 |
Species |
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
KEGG Pathway |
cne:CNF01620 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CS02
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CS02-F1 | Predicted | AlphaFoldDB |
No variants for P0CS02
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0CS02 | |||||
No associated diseases with P0CS02
No regional properties for P0CS02
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P0CS02 | |||
Functions
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic vesicle membrane | The lipid bilayer surrounding a cytoplasmic vesicle. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| antiporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). |
| GDP-mannose transmembrane transporter activity | Enables the transfer of a GDP-mannose from one side of a membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate transport | The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKPFVPTPN | ISRPATPSSL | DYGKDEASST | LLRDMGERGD | RERKDREERD | KKEAMPSGQD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QVLPILSYCA | ASIMMTVVNK | YVVSGANFTM | TFLLLAIQSS | VCVLAVTTVK | KLGFISFRDF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DKNDAKAWWP | ISTLLVAVIY | TGSKALQFLS | IPVYTIFKNL | TIILIAYGEV | FMFNGAVSGL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TLCSFALMVG | SSIIAAWSDI | TSVWNKEPEL | DPITGLEITV | GPVSTIGGLN | AGYIWMALNC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FVSAAYVLFM | RKRIKVTGFK | DWDSMYYNNL | LSIPILVVFS | LVIEDWGSES | LALNFPASNR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VLLLSAMAFS | GAAAVFISYS | TAWCVRITGS | TTYSMVGALN | KLPVAASGIL | FFGDPANFGN |
| 370 | 380 | 390 | |||
| ISAIAVGGVA | GVVYAVAKTN | QAKVEKARQA | RAAGGRP |