P0CR39

PR
Gene name
SEC23 (CNBJ2310)
Protein name
Protein transport protein SEC23
Names
Species
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)
KEGG Pathway
cnb:CNBJ2310
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

173-251 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0CR39

Entry ID Method Resolution Chain Position Source
AF-P0CR39-F1 Predicted AlphaFoldDB

No variants for P0CR39

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0CR39

No associated diseases with P0CR39

6 regional properties for P0CR39

Type Name Position InterPro Accession
domain Zinc finger, Sec23/Sec24-type 53 - 93 IPR006895
domain Sec23/Sec24, trunk domain 123 - 386 IPR006896
domain Sec23/Sec24, helical domain 513 - 611 IPR006900
domain Gelsolin-like domain 626 - 713 IPR007123
domain Sec23/Sec24 beta-sandwich 398 - 498 IPR012990
domain Sec23, C-terminal 606 - 725 IPR037550

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
COPII vesicle coat One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

1 GO annotations of molecular function

Name Definition
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
COPII-coated vesicle budding The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNFEDIEDKD GVRFSWNVWP SSRLEATRTV VPISALYTPL KEREDLPPVM YEPVTCKGSS
70 80 90 100 110 120
CKAILNPYCQ VDVRGKMWIC PFCLQRNPFP PHYHQDLSPN NLPPELLPKF TTIEYTLSRP
130 140 150 160 170 180
AQIPPIFLYV VDTCVDEDEL KALKETLVVS LSLLPPNALV GLITYGTMAM VHELAYADCP
190 200 210 220 230 240
KAYVFRGSKD YQPKQIADML GLNPSNRPIQ PVRPGQPMPA PAASKFLMPV QACEFQLTNI
250 260 270 280 290 300
LEQLQRDPWP VEQDKRPLRC TGVALSVAVS LLETAFPNTG ARIMLFSGGP ATDGPGMVVG
310 320 330 340 350 360
PELREPIRSH HDIDRDSVKH FKRASKFYEA LSKRASVNGH AIDIYAGCLD QVGLLEMKSL
370 380 390 400 410 420
TNATNGVMTI SDSFMTAIFK QSFLRTLGKD EQGYLKMGFN ATYDVLTTKE LKISGVIGHV
430 440 450 460 470 480
ISANKKSSCV GETEIGIGQT SAWKVCSLTP KSTLATYFEV VTPAGQALTP NQSGLIQFVT
490 500 510 520 530 540
HYQHSSGQYR LRVTTVSRVF QEGGHPSIAA SFDQEAAAVL MARIAVFKAE IDDSPDVLRW
550 560 570 580 590 600
LDRMLIRLCQ KFADYRKEDP TSFQLSPNFS IYPQFMFHLR RSQFLQVFNN SPDETAFYRH
610 620 630 640 650 660
VLNDSDVNNS LIMIQPTLMS YGFDSEPHPV LLDSVSIRPD VILLLDTFFH ILIFHGETIA
670 680 690 700 710 720
QWRKANYQEQ EDYANFKELL EAPIGDAQEL LEDRMPIPRY VVCDQGGSQA RFLLSKLNPS
730 740 750 760
TTHMSGSNYG AGPAGGQAIF TDDVSLQVFM EHLKRLAVGA STS