P0CR06
Gene name |
DBP10 (CNB00610) |
Protein name |
ATP-dependent RNA helicase DBP10 |
Names |
|
Species |
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
KEGG Pathway |
cne:CNB00610 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CR06
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CR06-F1 | Predicted | AlphaFoldDB |
No variants for P0CR06
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0CR06 | |||||
No associated diseases with P0CR06
1 regional properties for P0CR06
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Fungal lipase-like domain | 215 - 374 | IPR002921 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| identical protein binding | Binding to an identical protein or proteins. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| assembly of large subunit precursor of preribosome | The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome. |
| maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAITPSWAL | ETTADGEVKE | KTSGPGGQWR | ALNVGPDLIR | SLLIRKFKTP | TPIQRAAIPP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ALSTPPRDIL | GMARTGSGKT | LAYLIPLLQR | TGSTHHGQGP | RALILCPSRE | LAVQIYTVGK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DLARGMNKGK | GKGKNKNEDE | EDEEGKGKEG | LRWALIIGGE | GMDAQFEKMS | SNPDIVIATP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GRFLHLIVEM | HMDLRHLQTV | IYDEADRLFE | MGFDVQLQEI | LHRLPSTRQN | LLFSATLPSS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VAEFAKAGLV | NPLLVRLDAE | QKISPDLALK | FFSVKPGEKE | ASLLVLLREV | IGKPNQPEPA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DPSSAPQAIV | FVATKHHVDY | VAELLRTTGY | RTSLIYSSLD | QVARQQQLAG | FRSHQSDVLV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VTDVAARGLD | IPIMDHVINY | DFPAGPRIFV | HRVGRTARAG | RKGTAYSLIV | KEDFPYLCDL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| HTFLGTERMG | EPADVLRSLP | IEQLSENVEY | VFHNLDETAP | HITALRNVMR | KGQGMFERSR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TKANPTSYRQ | AKSLASALSN | NPPRIDDMFE | DAMEVEVNEE | KARLLAKVAA | FTPSETVFEV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GKRESESAII | MKKRRKTVDE | RQKRVSKAEA | EKSTASGMEK | APVKELPAPQ | LPSKNFKDPS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| FYLDHTQRGA | EAEKGYSLKS | GVESLSGAIT | DMTADEGTGP | KAQKASQLSW | DRKKHKFIKK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| NGSADGEKMI | KSESGALLPA | SYSSGKYQEW | KSKRRHMPDG | PVEALALGGG | RRGRHGPPGQ |
| 730 | 740 | 750 | 760 | 770 | 780 |
| KRKAEDGDGG | EDAGGKGRKD | QGKSKGTGKG | KDDFKQKSPG | KPGKKGIKQS | SGLKSAMDIR |
| 790 | 800 | ||||
| KQREIAQKRK | EKNARKPQKF | RK |