P0CQ72
Gene name |
FAL1 (CNC06360) |
Protein name |
ATP-dependent RNA helicase FAL1 |
Names |
|
Species |
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
KEGG Pathway |
cne:CNC06360 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CQ72
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CQ72-F1 | Predicted | AlphaFoldDB |
No variants for P0CQ72
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0CQ72 | |||||
No associated diseases with P0CQ72
8 regional properties for P0CQ72
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RNA polymerase sigma-70 | 91 - 104 | IPR000943-1 |
| domain | RNA polymerase sigma-70 | 236 - 248 | IPR000943-2 |
| domain | RNA polymerase sigma-70 | 253 - 268 | IPR000943-3 |
| domain | RNA polymerase sigma-70 | 268 - 279 | IPR000943-4 |
| domain | RNA polymerase sigma-70 region 3 | 146 - 209 | IPR007624 |
| domain | RNA polymerase sigma-70 region 2 | 67 - 136 | IPR007627 |
| domain | RNA polymerase sigma-70 region 4 | 232 - 280 | IPR007630 |
| domain | RNA polymerase sigma-70 like domain | 64 - 281 | IPR014284 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| catalytic step 2 spliceosome | A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGVNVGDDK | LVFESSEAVT | VAPTFEALNL | KEDLLRGIYA | YNFEKPSAIQ | QRAIIPIIRG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RDVIAQAQSG | TGKTATFSIS | MLQSIDTNLR | ETQALVLSPT | RELAVQIQTV | VLALGDYMNV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SCHACIGGTS | VGEDIRKLEA | GQQVVSGTPG | RVFDMIRRRN | LRTKDIKMLI | LDESDELLNK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GFKDQIYDIY | RYLPPATQVV | VVSATLPHDV | LEMTTKFMTD | PVRILVKRDE | LTLEGIKQFF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VAVEKEDWKF | DTLCDLYDTL | TITQAVIFCN | TRRKVDWLTE | KMREANFTVS | SMHGEMVQKE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RDAIMAEFRG | GQSRVLITTD | VWARGIDVQQ | VSLVINYDLP | TSRENYLHRI | GRSGRFGRKG |
| 370 | 380 | 390 | |||
| VAINFVTVDD | VRILRDIEQY | YSTQIDEMPM | NVAELT |