P0CQ03
Gene name |
RRD2 (CNBL1550) |
Protein name |
Serine/threonine-protein phosphatase 2A activator 2 |
Names |
Peptidyl-prolyl cis-trans isomerase PTPA-2, PPIase PTPA-2, Rotamase PTPA-2, Phosphotyrosyl phosphatase activator 2 |
Species |
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans) |
KEGG Pathway |
cnb:CNBL1550 |
EC number |
5.2.1.8: Cis-trans isomerases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CQ03
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CQ03-F1 | Predicted | AlphaFoldDB |
No variants for P0CQ03
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0CQ03 | |||||
No associated diseases with P0CQ03
No regional properties for P0CQ03
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P0CQ03 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 5.2.1.8 | Cis-trans isomerases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| peptidyl-prolyl cis-trans isomerase activity | Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). |
| phosphatase activator activity | Binds to and increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAPESSPST | FYTVPTKHIL | SKAHLAAFQR | SKTHSDIFNF | IEELNEDIVG | KKLTEAGQGS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ERTRPLISIL | DSVREIAEST | PPVDNKLSRF | GNPAFKTFYD | KVGDASLELH | KRIPGLPEEA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IQEVEVYFKE | SWGNKQRVDY | GSGMELNFLS | WLLCLAKLGV | VTKEDYPFLV | LGVFWRYIEV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MRYLQSTYWL | EPAGSHGVWG | LDDYHFLPFL | WGSGQLRNHK | YLRPKAIHDP | EILGEFSKDY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MYLSCIEFIN | SIKTASLRWH | SPMLDDISAV | KTWEKVNQGM | KKMFVAEVLG | KLPVMQHALF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GSLLPFPTPE | EDPELKRALE | EEDGQSATDM | HGHIHDPSEK | GWSMDCCGIP | VPSAFAAAQD |
| 370 | 380 | ||||
| ANSHKGVPTL | GNRPGIKPIP | FD |