P0CO63
Gene name |
PPE1 (CNBH2760) |
Protein name |
Protein phosphatase methylesterase 1 |
Names |
PME-1 |
Species |
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans) |
KEGG Pathway |
cnb:CNBH2760 |
EC number |
3.1.1.89: Carboxylic ester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CO63
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CO63-F1 | Predicted | AlphaFoldDB |
No variants for P0CO63
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0CO63 | |||||
No associated diseases with P0CO63
1 regional properties for P0CO63
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Alpha/beta hydrolase fold-1 | 123 - 383 | IPR000073 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.1.89 | Carboxylic ester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein methylesterase activity | Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein demethylation | The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSDMFRKSVL | NKLPHLPPTR | APWADESEPI | EEIDEEDEQL | DGIGEFKPAT | MGPSKHDTQD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YSPLSASTFF | AQAAEVQPPS | TPCTFRVYLT | PPNLSIASTN | AGTPPGPSGL | RTQQQTNRHG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TYLVCHHGGG | ASGLGFAPLA | REVKAKGNGE | MGVLAFDCRG | HGKTSTSDPN | LELDLSHDTL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LSDFMAIIEM | MFPDPKESPS | LILLGHSMGA | APVVSAAPEL | QKKGYTIPGV | VVLDVVEGTA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VESLPLMKSV | LSKRPESFRS | VIDAIYWHVT | SNSIRNVESA | RVSVPHIIVP | APSSSSSDPS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ANPGGKQVWR | TNLVGTEPYW | EGWYKGLSQR | FLRTKCARLL | VLAGQERLDR | ELMVGQMQGK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FQLEVMSDVG | HYLHEDNPAG | LAATLITFWH | RNTRVLVLPP | KIGAPGPGAR | GGPVEVKQVG |