P0CN99

PR
Gene name
HTA1 (CNBB5150)
Protein name
Histone H2A
Names
Species
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)
KEGG Pathway
cnb:CNBB5150
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-48 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0CN99

Entry ID Method Resolution Chain Position Source
AF-P0CN99-F1 Predicted AlphaFoldDB

No variants for P0CN99

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0CN99

No associated diseases with P0CN99

3 regional properties for P0CN99

Type Name Position InterPro Accession
domain Histone H2A/H2B/H3 10 - 89 IPR007125
domain Histone H2A, C-terminal domain 92 - 126 IPR032454
conserved_site Histone H2A conserved site 22 - 28 IPR032458

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Chromosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
protein heterodimerization activity Binding to a nonidentical protein to form a heterodimer.
structural constituent of chromatin The action of a molecule that contributes to the structural integrity of chromatin.

1 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSGGKGKAS SETKSSSRSS KAGLQFPVGR IHRLLKKGNY AQRIGSGAPV YLAAVLEYLA
70 80 90 100 110 120
AEILELAGNA ARDNKKSRIV PRHLQLAVRN DEELNKLLGS VVISQGGVLP HIMAELLPVK
130
TKGKAKASQE V