P0CN34

PR
Gene name
EFG1 (CNN01370)
Protein name
rRNA-processing protein EFG1
Names
Species
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-81 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0CN34

Entry ID Method Resolution Chain Position Source
AF-P0CN34-F1 Predicted AlphaFoldDB

No variants for P0CN34

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0CN34

No associated diseases with P0CN34

4 regional properties for P0CN34

Type Name Position InterPro Accession
domain SANT/Myb domain 201 - 250 IPR001005
domain Signal transduction response regulator, receiver domain 11 - 127 IPR001789
domain Myb domain, plants 198 - 251 IPR006447
domain Myb domain 195 - 254 IPR017930

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
preribosome, small subunit precursor A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPADKKQRKG AHPYRKPRPN PSDPSSSDKP ARPKPTHRIP ATEARDGAGI PGLSKLKSSI
70 80 90 100 110 120
RQTKRLLAKE NLEPGLRVST QRRLTSLEAD LAAAERREVE RKNGAKYHKV KFFERQKLVR
130 140 150 160 170 180
LIKRFKRKLL DSETSSKKRS KHEEELLDAR IMLNYVLHYP NTQKYISLFP SNPNQTEDED
190 200 210 220 230 240
DDDDSSKPKL KLPPLLHPVP STEECEKMDK PTKRRYDLLL ETKRLMEESK LKSEPETDLK
250 260 270 280
KGQVDGVVVG LGADVQIGLG DKKEAKQNAA QGTGEEEDDF FESGDE