P0CM09
Gene name |
YAF9 (CNBH3860) |
Protein name |
Protein AF-9 homolog |
Names |
|
Species |
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans) |
KEGG Pathway |
cnb:CNBH3860 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CM09
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CM09-F1 | Predicted | AlphaFoldDB |
No variants for P0CM09
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0CM09 | |||||
No associated diseases with P0CM09
No regional properties for P0CM09
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P0CM09 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| NuA4 histone acetyltransferase complex | A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60). |
| Swr1 complex | A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSERVRGIQ | VHRPIIFGSH | ARLLTEAEKQ | LAPAGHTHKW | TVFLNSAASP | PLKQGEPPDY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EDIDYLPGGA | DDLSYFIRKV | TFKLHETYAT | PNRVIDKPPY | RVSETGWGEF | TVQIRIQLIP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ESSEKPLGLQ | HNIKLHHWGA | PVEPLPVVSG | APTPTPVPTE | SNTEVKLEPD | TPAPLEESVT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PAPTIQRPAS | EPATNEPGSN | QGTPAPPGGD | STEQIKVDVA | TPALEVIEPS | ATPAPLSLAA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RLPIHAWQYD | EIVFSDPPRQ | FLDILNAHPP | TPLPAKSRRP | RDQREDYEAR | KKGKSAARGA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SVTASARASR | AGTVDTAAAG | TPAPAQIGIP | GEPGSADVPL | EFTQEMLKGE | HNAMLDARVK |
| 370 | 380 | 390 | |||
| IVEQMDRWRE | RLIALEKELA | KAKEDVKATA | AM |