Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CL83
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CL83-F1 | Predicted | AlphaFoldDB |
No variants for P0CL83
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0CL83 | |||||
No associated diseases with P0CL83
1 regional properties for P0CL83
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Stromalin conservative domain | 10 - 95 | IPR020839 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromatin | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
| cohesin complex | A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3). |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| chromatin binding | Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| sister chromatid cohesion | The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIFSMLRKLP | KVTCRDVLPE | IRAICIEEIG | CWMQSYSTSF | LTDSYLKYIG | WTLHDKHREV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RVKCVKALKG | LYGNRDLTAR | LELFTGRFKD | WMVSMIVDRE | YSVAVEAVRL | LILILKLFYP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ECEIRTMGGR | EQRQSPGAQR | TFFQLLLSFF | VESKLHDHAA | YLVDNLWDCA | GTQLKDWEGL |
| 190 | 200 | ||||
| TSLLLEKDQS | TCHMEPGPGT | FHLLG |